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Single point mutations reveal amino acid residues important for Chromobacterium violaceum transaminase activity in the production of unnatural amino acids

Unnatural amino acids (UAAs) are chiral amines with high application potential in drug discovery and synthesis of other valuable chemicals. Biocatalysis offers the possibility to synthesise novel optically pure UAAs with different physical and chemical properties. While the biocatalytic potential of...

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Detalles Bibliográficos
Autores principales: Almahboub, Sarah A., Narancic, Tanja, Fayne, Darren, O’Connor, Kevin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255834/
https://www.ncbi.nlm.nih.gov/pubmed/30478262
http://dx.doi.org/10.1038/s41598-018-35688-7