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Single point mutations reveal amino acid residues important for Chromobacterium violaceum transaminase activity in the production of unnatural amino acids
Unnatural amino acids (UAAs) are chiral amines with high application potential in drug discovery and synthesis of other valuable chemicals. Biocatalysis offers the possibility to synthesise novel optically pure UAAs with different physical and chemical properties. While the biocatalytic potential of...
Autores principales: | Almahboub, Sarah A., Narancic, Tanja, Fayne, Darren, O’Connor, Kevin E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255834/ https://www.ncbi.nlm.nih.gov/pubmed/30478262 http://dx.doi.org/10.1038/s41598-018-35688-7 |
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