Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis

This is the first study to investigate the hepatoprotective effect of CQ on acute liver injury caused by carbon tetrachloride (CCl(4)) in a murine model and the underlying molecular mechanisms. Ninety-six mice were randomly divided into the control (n = 8), CQ (n = 8), CCl(4) (n = 40), and CCl(4) + ...

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Detalles Bibliográficos
Autores principales: Dai, Chongshan, Xiao, Xilong, Li, Daowen, Tun, Sun, Wang, Ying, Velkov, Tony, Tang, Shusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255886/
https://www.ncbi.nlm.nih.gov/pubmed/30478280
http://dx.doi.org/10.1038/s41419-018-1136-2

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