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A Vaccine Based on a Modified Vaccinia Virus Ankara Vector Expressing Zika Virus Structural Proteins Controls Zika Virus Replication in Mice
Zika virus (ZIKV) is a re-emerging mosquito-borne flavivirus that affects humans and can cause severe neurological complications, including Guillain-Barré syndrome and microcephaly. Since 2007 there have been three large outbreaks; the last and larger spread in the Americas in 2015. Actually, ZIKV i...
Autores principales: | Pérez, Patricia, Q. Marín, María, Lázaro-Frías, Adrián, Jiménez de Oya, Nereida, Blázquez, Ana-Belén, Escribano-Romero, Estela, S. Sorzano, Carlos Óscar, Ortego, Javier, Saiz, Juan-Carlos, Esteban, Mariano, Martín-Acebes, Miguel A., García-Arriaza, Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255889/ https://www.ncbi.nlm.nih.gov/pubmed/30478418 http://dx.doi.org/10.1038/s41598-018-35724-6 |
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