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Calcimimetic restores diabetic peripheral neuropathy by ameliorating apoptosis and improving autophagy
Decreased AMPK-eNOS bioavailability mediates the development of diabetic peripheral neuropathy (DPN) through increased apoptosis and decreased autophagy activity in relation to oxidative stress. Schwann cells are responsible for maintaining structural and functional integrity of neurons and for repa...
Autores principales: | Chung, You Chul, Lim, Ji Hee, Oh, Hyun Mi, Kim, Hyung Wook, Kim, Min Young, Kim, Eun Nim, Kim, Yaeni, Chang, Yoon Sik, Kim, Hye Won, Park, Cheol Whee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255917/ https://www.ncbi.nlm.nih.gov/pubmed/30478254 http://dx.doi.org/10.1038/s41419-018-1192-7 |
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