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Opposing Effects on Vascular Smooth Muscle Cell Proliferation and Macrophage-induced Inflammation Reveal a Protective Role for the Proresolving Lipid Mediator Receptor ChemR23 in Intimal Hyperplasia

Intimal hyperplasia remains a significant clinical problem in for example coronary artery bypass graft failure. Since omega-3 fatty acids reduce intimal hyperplasia, we hypothesized that the G protein-coupled receptor ChemR23 for the omega-3-derived pro-resolving lipid mediator resolvin E1 drives th...

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Detalles Bibliográficos
Autores principales:	Artiach, Gonzalo, Carracedo, Miguel, Clària, Joan, Laguna-Fernandez, Andres, Bäck, Magnus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255922/ https://www.ncbi.nlm.nih.gov/pubmed/30515096 http://dx.doi.org/10.3389/fphar.2018.01327

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