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Therapeutic Targeting of IRFs: Pathway-Dependence or Structure-Based?
The interferon regulatory factors (IRFs) are a family of master transcription factors that regulate pathogen-induced innate and acquired immune responses. Aberration(s) in IRF signaling pathways due to infection, genetic predisposition and/or mutation, which can lead to increased expression of type...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255967/ https://www.ncbi.nlm.nih.gov/pubmed/30515152 http://dx.doi.org/10.3389/fimmu.2018.02622 |