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Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury
In toxicogenomics, functional annotation is an important step to gain additional insights into genes with aberrant expression that drive pathophysiological mechanisms. Nevertheless, there exists a gap on annotation of these genes which often hampers the interpretation of results and limits their app...
Autores principales: | Souza, Terezinha, Trairatphisan, Panuwat, Piñero, Janet, Furlong, Laura I., Saez-Rodriguez, Julio, Kleinjans, Jos, Jennen, Danyel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255978/ https://www.ncbi.nlm.nih.gov/pubmed/30515189 http://dx.doi.org/10.3389/fgene.2018.00527 |
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