IVIg and LPS Co-stimulation Induces IL-10 Production by Human Monocytes, Which Is Compromised by an FcγRIIA Disease-Associated Gene Variant

Intravenous Immunoglobulin (IVIg) is used to treat autoimmune or inflammatory diseases, but its mechanism of action is not completely understood. We asked whether IVIg can induce interleukin-10 (IL-10) and reduce pro-inflammatory cytokine production in human monocytes, and whether this response is r...

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Detalles Bibliográficos
Autores principales: Kozicky, Lisa K., Menzies, Susan C., Zhao, Zheng Yu, Vira, Tariq, Harnden, Kiera, Safari, Kwestan, Del Bel, Kate L., Turvey, Stuart E., Sly, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255983/
https://www.ncbi.nlm.nih.gov/pubmed/30515163
http://dx.doi.org/10.3389/fimmu.2018.02676

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