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The impact of CYP2D6 mediated drug–drug interaction: a systematic review on a combination of metoprolol and paroxetine/fluoxetine

AIM: Metoprolol (a CYP2D6 substrate) is often co‐prescribed with paroxetine/fluoxetine (a CYP2D6 inhibitor) because the clinical relevance of this drug–drug interaction (DDI) is still unclear. This review aimed to systematically evaluate the available evidence and quantify the clinical impact of the...

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Detalles Bibliográficos
Autores principales:	Bahar, Muh. Akbar, Kamp, Jasper, Borgsteede, Sander D., Hak, Eelko, Wilffert, Bob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Systematic Review and Meta‐analysis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255988/ https://www.ncbi.nlm.nih.gov/pubmed/30248178 http://dx.doi.org/10.1111/bcp.13741

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