A Subset of Exoribonucleases Serve as Degradative Enzymes for pGpG in c-di-GMP Signaling

Bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) is a bacterial second messenger that regulates processes, such as biofilm formation and virulence. During degradation, c-di-GMP is first linearized to 5′-phosphoguanylyl-(3′,5′)-guanosine (pGpG) and subsequently hydrolyzed to two GMPs by a previously unknown...

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Detalles Bibliográficos
Autores principales: Orr, Mona W., Weiss, Cordelia A., Severin, Geoffrey B., Turdiev, Husan, Kim, Soo-Kyoung, Turdiev, Asan, Liu, Kuanqing, Tu, Benjamin P., Waters, Christopher M., Winkler, Wade C., Lee, Vincent T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256023/
https://www.ncbi.nlm.nih.gov/pubmed/30249708
http://dx.doi.org/10.1128/JB.00300-18

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