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Food‐effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers

AIMS: This study aimed to determine the effect of food intake on uracil and dihydrouracil plasma levels. These levels are a promising marker for dihydropyrimidine dehydrogenase activity and for individualizing fluoropyrimidine anticancer therapy. METHODS: A randomized, cross‐over study in 16 healthy...

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Detalles Bibliográficos
Autores principales:	Henricks, Linda M., Jacobs, Bart A. W., Meulendijks, Didier, Pluim, Dick, van den Broek, Daan, de Vries, Niels, Rosing, Hilde, Beijnen, Jos H., Huitema, Alwin D. R., Guchelaar, Henk‐Jan, Cats, Annemieke, Schellens, Jan H. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256055/ https://www.ncbi.nlm.nih.gov/pubmed/30047584 http://dx.doi.org/10.1111/bcp.13719

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