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Dose-Dependent Effects of Insulin-Like Growth Factor 1 in the Aged Olfactory Epithelium

Background: Olfaction is known to be impaired by aging. We hypothesized that insulin-like growth factor-1 (IGF-1) administered at an appropriate dose could prevent age-induced negative effects on olfactory receptor neurons (ORNs). We explored the effects of low- and high-dose administration of IGF-1...

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Detalles Bibliográficos
Autores principales:	Ueha, Rumi, Kondo, Kenji, Ueha, Satoshi, Yamasoba, Tatsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256067/ https://www.ncbi.nlm.nih.gov/pubmed/30515092 http://dx.doi.org/10.3389/fnagi.2018.00385

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