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Inflammation and Mechanical Stress Stimulate Osteogenic Differentiation of Human Aortic Valve Interstitial Cells

Background: Aortic valve calcification is an active proliferative process, where interstitial cells of the valve transform into either myofibroblasts or osteoblast-like cells causing valve deformation, thickening of cusps and finally stenosis. This process may be triggered by several factors includi...

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Detalles Bibliográficos
Autores principales:	Bogdanova, Maria, Kostina, Aleksandra, Zihlavnikova Enayati, Katarina, Zabirnyk, Arsenii, Malashicheva, Anna, Stensløkken, Kåre-Olav, Sullivan, Gareth John, Kaljusto, Mari-Liis, Kvitting, John-Peder Escobar, Kostareva, Anna, Vaage, Jarle, Rutkovskiy, Arkady
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256176/ https://www.ncbi.nlm.nih.gov/pubmed/30524301 http://dx.doi.org/10.3389/fphys.2018.01635

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