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Microphysiologic Human Tissue Constructs Reproduce Autologous Age-Specific BCG and HBV Primary Immunization in vitro
Current vaccine development disregards human immune ontogeny, relying on animal models to select vaccine candidates targeting human infants, who are at greatest risk of infection worldwide, and receive the largest number of vaccines. To help accelerate and de-risk development of early-life effective...
Autores principales: | Sanchez-Schmitz, Guzman, Stevens, Chad R., Bettencourt, Ian A., Flynn, Peter J., Schmitz-Abe, Klaus, Metser, Gil, Hamm, David, Jensen, Kristoffer J., Benn, Christine, Levy, Ofer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256288/ https://www.ncbi.nlm.nih.gov/pubmed/30524426 http://dx.doi.org/10.3389/fimmu.2018.02634 |
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