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Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes
[Image: see text] Current molecular hypotheses have not yet delivered marketable treatments for Alzheimer’s disease (AD), arguably due to a lack of understanding of AD biology and an overreliance on conventional drug modalities. Protein–protein interactions (PPIs) are emerging drug targets, which sh...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256345/ https://www.ncbi.nlm.nih.gov/pubmed/29722962 http://dx.doi.org/10.1021/acschemneuro.8b00118 |