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OnPLS-Based Multi-Block Data Integration: A Multivariate Approach to Interrogating Biological Interactions in Asthma

[Image: see text] Integration of multiomics data remains a key challenge in fulfilling the potential of comprehensive systems biology. Multiple-block orthogonal projections to latent structures (OnPLS) is a projection method that simultaneously models multiple data matrices, reducing feature space w...

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Detalles Bibliográficos
Autores principales: Reinke, Stacey N., Galindo-Prieto, Beatriz, Skotare, Tomas, Broadhurst, David I., Singhania, Akul, Horowitz, Daniel, Djukanović, Ratko, Hinks, Timothy S.C., Geladi, Paul, Trygg, Johan, Wheelock, Craig E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256348/
https://www.ncbi.nlm.nih.gov/pubmed/30335973
http://dx.doi.org/10.1021/acs.analchem.8b03205