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Facile chemoenzymatic synthesis of a novel stable mimic of NAD(+)

Nicotinamide adenine dinucleotide (NAD(+)) is an essential cofactor participating in a variety of important enzyme-catalyzed physiological and pathophysiological processes. Analogues of NAD(+) provide key and valuable agents for investigating NAD(+)-dependent enzymes. In this study, we report the pr...

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Detalles Bibliográficos
Autores principales: Dai, Zhefu, Zhang, Xiao-Nan, Nasertorabi, Fariborz, Cheng, Qinqin, Pei, Hua, Louie, Stan G., Stevens, Raymond C., Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256357/
https://www.ncbi.nlm.nih.gov/pubmed/30568770
http://dx.doi.org/10.1039/c8sc03899f