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Shear stress induces expression, intracellular reorganization and enhanced Notch activation potential of Jagged1

Notch signaling and blood flow regulate vascular formation and maturation, but how shear stress affects the different components of the Notch pathway in endothelial cells is poorly understood. We show that laminar shear stress results in a ligand specific gene expression profile in endothelial cells...

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Detalles Bibliográficos
Autores principales:	Driessen, R. C. H., Stassen, O. M. J. A., Sjöqvist, M., Suarez Rodriguez, F., Grolleman, J., Bouten, C. V. C., Sahlgren, C. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256362/ https://www.ncbi.nlm.nih.gov/pubmed/30328449 http://dx.doi.org/10.1039/c8ib00036k

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