Cargando…

FK866 inhibits the epithelial-mesenchymal transition of hepatocarcinoma MHCC97-H cells

Epithelial-mesenchymal transition (EMT) is known to serve a pivotal function in hepatocellular carcinoma (HCC) metastasis. Nicotinamide phosphoribosyltransferase (NAMPT), the key enzyme in the nicotinamide-adenine dinucleotide (NAD(+))-mediated pathway for the activation of silent information regula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Bin, Shi, Dongmei, Zhang, Xiangyu, Liang, Guanzhao, Liu, Weida, Qiao, Sen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256367/ https://www.ncbi.nlm.nih.gov/pubmed/30546461 http://dx.doi.org/10.3892/ol.2018.9541

Ejemplares similares

The NAMPT inhibitor FK866 reverts the damage in spinal cord injury
por: Esposito, Emanuela, et al.
Publicado: (2012)

Phosphoproteomic Analysis of the Highly-Metastatic Hepatocellular Carcinoma Cell Line, MHCC97-H
por: Tian, Miaomiao, et al.
Publicado: (2015)

A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT
por: Barraud, Marine, et al.
Publicado: (2016)

The NAMPT Inhibitor FK866 Increases Metformin Sensitivity in Pancreatic Cancer Cells
por: Parisotto, Maxime, et al.
Publicado: (2022)

The NAMPT Inhibitor FK866 in Combination with Cisplatin Reduces Cholangiocarcinoma Cells Growth
por: Pant, Kishor, et al.
Publicado: (2023)

Downregulation of B7-H4 in the MHCC97-H hepatocellular carcinoma cell line by arsenic trioxide
por: CUI, LIMING, et al.
Publicado: (2016)

Cross resistance to diverse anticancer nicotinamide phosphoribosyltransferase inhibitors induced by FK866 treatment
por: Ogino, Yoko, et al.
Publicado: (2018)

Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells
por: Thakur, Basant Kumar, et al.
Publicado: (2013)

IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells
por: Maleki Vareki, Saman, et al.
Publicado: (2015)

Synthesis and Evaluation of Reactive Oxygen Species Sensitive Prodrugs of a NAMPT Inhibitor FK866
por: Xu, Zili, et al.
Publicado: (2022)

Myricetin inhibits migration and invasion of hepatocellular carcinoma MHCC97H cell line by inhibiting the EMT process
por: Ma, Hongxin, et al.
Publicado: (2019)

Neuroprotective effects of FK866 against traumatic brain injury: Involvement of p38/ERK pathway
por: Tan, Zhongju, et al.
Publicado: (2020)

FK866 Protects Human Dental Pulp Cells against Oxidative Stress-Induced Cellular Senescence
por: Ok, Chang Youp, et al.
Publicado: (2021)

The effect of bone marrow mesenchymal stem cells on highly metastatic MHCC97-H hepatocellular carcinoma cells following OPN and TGFβ1 gene silencing
por: Zhang, Beibei, et al.
Publicado: (2020)

Casticin inhibits self-renewal of liver cancer stem cells from the MHCC97 cell line
por: HE, GUICHENG, et al.
Publicado: (2014)

Triptolide Inhibits Invasion and Tumorigenesis of Hepatocellular Carcinoma MHCC-97H Cells Through NF-κB Signaling
por: Wang, Haiji, et al.
Publicado: (2016)

HMGA1 participates in MHCC97H cell proliferation and invasion through the ILK/Akt/GSK3β signaling pathway
por: Liu, Li, et al.
Publicado: (2017)

MC-PPEA as a new and more potent inhibitor of CLP-induced sepsis and pulmonary inflammation than FK866
por: Huang, Peixin, et al.
Publicado: (2017)

FK866 attenuates acute hepatic failure through c-jun-N-terminal kinase (JNK)-dependent autophagy
por: Guo, Enshuang, et al.
Publicado: (2017)

Both Talin-1 and Talin-2 correlate with malignancy potential of the human hepatocellular carcinoma MHCC-97 L cell
por: Fang, Kun-peng, et al.
Publicado: (2016)

MicroRNA-30a-3p acts as a tumor suppressor in MHCC-97H hepatocellular carcinoma cells by targeting COX-2
por: Yang, XueMei, et al.
Publicado: (2021)

Transcriptome analysis of the effect of a novel human serine protease inhibitor SPINK13 on gene expression in MHCC97-H cells
por: Wei, Ling, et al.
Publicado: (2021)

A Nicotinamide Phosphoribosyltransferase Inhibitor, FK866, Suppresses the Growth of Anaplastic Meningiomas and Inhibits Immune Checkpoint Expression by Regulating STAT1
por: Deng, Yuxuan, et al.
Publicado: (2022)

MicroRNA-30a-3p acts as a tumor suppressor in MHCC-97H hepatocellular carcinoma cells by targeting COX-2: Erratum
por: Yang, XueMei, et al.
Publicado: (2022)

Cordyceps cicadae induces G2/M cell cycle arrest in MHCC97H human hepatocellular carcinoma cells: a proteomic study
por: Wang, Hualin, et al.
Publicado: (2014)

Knockdown of yes-associated protein inhibits proliferation and downregulates large tumor suppressor 1 expression in MHCC97H human hepatocellular carcinoma cells
por: WANG, CHENG, et al.
Publicado: (2015)

The Effects of a Novel Curcumin Derivative Loaded Long-Circulating Solid Lipid Nanoparticle on the MHCC-97H Liver Cancer Cells and Pharmacokinetic Behavior
por: Wei, Yumeng, et al.
Publicado: (2022)

MicroRNA-34a-5p enhances sensitivity to chemotherapy by targeting AXL in hepatocellular carcinoma MHCC-97L cells
por: LI, XIAO-YUN, et al.
Publicado: (2015)

Survivin downregulation using siRNA nanoliposomes inhibits cell proliferation and promotes the apoptosis of MHCC-97H hepatic cancer cells: An in vitro and in vivo study
por: Liu, Ziqin, et al.
Publicado: (2017)

Extracellular HSP70/HSP70-PCs Promote Epithelial-Mesenchymal Transition of Hepatocarcinoma Cells
por: Li, Hangyu, et al.
Publicado: (2013)

New human hepatocellular carcinoma (HCC) cell line with highly metastatic potential (MHCC97) and its expressions of the factors associated with metastasis
por: Tian, J, et al.
Publicado: (1999)

Characterization and Cytotoxicity of Polyprenol Lipid and Vitamin E-TPGS Hybrid Nanoparticles for Betulinic Acid and Low-Substituted Hydroxyl Fullerenol in MHCC97H and L02 Cells
por: Tao, Ran, et al.
Publicado: (2020)

Quantitative Analysis of Daporinad (FK866) and Its In Vitro and In Vivo Metabolite Identification Using Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry
por: Park, Minjae, et al.
Publicado: (2022)

Hydroxypyridinone-Coumarin Inhibits the Proliferation of MHCC97 and HepG2 Human Hepatocellular Carcinoma Cells and Down-Regulates the Phosphoinositide-3 Kinase Pathway
por: Cui, Xiaopeng, et al.
Publicado: (2020)

COLLABORATION AGREEMENT K 866
por: THE EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH, CERN, et al.
Publicado: (2002)

Crosstalk between Beta-Catenin and Snail in the Induction of Epithelial to Mesenchymal Transition in Hepatocarcinoma: Role of the ERK1/2 Pathway
por: Zucchini-Pascal, Nathalie, et al.
Publicado: (2013)

Knockdown of Urothelial Carcinoma-Associated 1 Suppressed Cell Growth and Migration Through Regulating miR-301a and CXCR4 in Osteosarcoma MHCC97 Cells
por: Zhu, Genglong, et al.
Publicado: (2018)

Autophagy induces transforming growth factor‐β‐dependent epithelial‐mesenchymal transition in hepatocarcinoma cells through cAMP response element binding signalling
por: Hu, Shaobo, et al.
Publicado: (2018)

Docetaxel-loaded lipid microbubbles combined with ultrasound-triggered microbubble destruction for targeted tumor therapy in MHCC-H cells
por: Zhang, Yue, et al.
Publicado: (2016)

Use of FK506 and bone marrow mesenchymal stem cells for rat hind limb allografts☆
por: Song, Youxin, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_m74gpqlforjuq10hm318dkon0r