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Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014
During 2013–2014, we collected 1,926 serum samples from humans and 4,583 ticks (Hyalomma asiaticum or Dermacentor nuttalli) in select regions of Mongolia to determine the risk for Crimean-Congo hemorrhagic fever virus (CCHFV) infection among humans in this country. Testing of human serum samples by...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256378/ https://www.ncbi.nlm.nih.gov/pubmed/30457521 http://dx.doi.org/10.3201/eid2412.180175 |
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author | Voorhees, Matthew A. Padilla, Susana L. Jamsransuren, Dulamjav Koehler, Jeffrey W. Delp, Korey L. Adiyadorj, Dolgorkhand Baasandagwa, Uyanga Jigjav, Battsetseg Olschner, Scott P. Minogue, Timothy D. Schoepp, Randal J. |
author_facet | Voorhees, Matthew A. Padilla, Susana L. Jamsransuren, Dulamjav Koehler, Jeffrey W. Delp, Korey L. Adiyadorj, Dolgorkhand Baasandagwa, Uyanga Jigjav, Battsetseg Olschner, Scott P. Minogue, Timothy D. Schoepp, Randal J. |
author_sort | Voorhees, Matthew A. |
collection | PubMed |
description | During 2013–2014, we collected 1,926 serum samples from humans and 4,583 ticks (Hyalomma asiaticum or Dermacentor nuttalli) in select regions of Mongolia to determine the risk for Crimean-Congo hemorrhagic fever virus (CCHFV) infection among humans in this country. Testing of human serum samples by ELISA demonstrated an overall CCHFV antibody prevalence of 1.4%; Bayankhongor Province had the highest prevalence, 2.63%. We pooled and analyzed tick specimens by real-time reverse transcription PCR; 1 CCHFV-positive H. asiaticum tick pool from Ömnögovi was identified. In phylogenetic analyses, the virus’s partial small segment clustered with CCHFV isolates from Central Asia, and the complete medium segment grouped with CCHFV isolates from Africa, Asia, and the Middle East. This study confirms CCHFV endemicity in Mongolia and provides information on risk for CCHFV infection. Further research is needed to better define the risk for CCHFV disease to improve risk mitigation, diagnostics, and surveillance. |
format | Online Article Text |
id | pubmed-6256378 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-62563782018-12-05 Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014 Voorhees, Matthew A. Padilla, Susana L. Jamsransuren, Dulamjav Koehler, Jeffrey W. Delp, Korey L. Adiyadorj, Dolgorkhand Baasandagwa, Uyanga Jigjav, Battsetseg Olschner, Scott P. Minogue, Timothy D. Schoepp, Randal J. Emerg Infect Dis Research During 2013–2014, we collected 1,926 serum samples from humans and 4,583 ticks (Hyalomma asiaticum or Dermacentor nuttalli) in select regions of Mongolia to determine the risk for Crimean-Congo hemorrhagic fever virus (CCHFV) infection among humans in this country. Testing of human serum samples by ELISA demonstrated an overall CCHFV antibody prevalence of 1.4%; Bayankhongor Province had the highest prevalence, 2.63%. We pooled and analyzed tick specimens by real-time reverse transcription PCR; 1 CCHFV-positive H. asiaticum tick pool from Ömnögovi was identified. In phylogenetic analyses, the virus’s partial small segment clustered with CCHFV isolates from Central Asia, and the complete medium segment grouped with CCHFV isolates from Africa, Asia, and the Middle East. This study confirms CCHFV endemicity in Mongolia and provides information on risk for CCHFV infection. Further research is needed to better define the risk for CCHFV disease to improve risk mitigation, diagnostics, and surveillance. Centers for Disease Control and Prevention 2018-12 /pmc/articles/PMC6256378/ /pubmed/30457521 http://dx.doi.org/10.3201/eid2412.180175 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Voorhees, Matthew A. Padilla, Susana L. Jamsransuren, Dulamjav Koehler, Jeffrey W. Delp, Korey L. Adiyadorj, Dolgorkhand Baasandagwa, Uyanga Jigjav, Battsetseg Olschner, Scott P. Minogue, Timothy D. Schoepp, Randal J. Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014 |
title | Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014 |
title_full | Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014 |
title_fullStr | Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014 |
title_full_unstemmed | Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014 |
title_short | Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014 |
title_sort | crimean-congo hemorrhagic fever virus, mongolia, 2013–2014 |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256378/ https://www.ncbi.nlm.nih.gov/pubmed/30457521 http://dx.doi.org/10.3201/eid2412.180175 |
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