Cargando…

Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014

During 2013–2014, we collected 1,926 serum samples from humans and 4,583 ticks (Hyalomma asiaticum or Dermacentor nuttalli) in select regions of Mongolia to determine the risk for Crimean-Congo hemorrhagic fever virus (CCHFV) infection among humans in this country. Testing of human serum samples by...

Descripción completa

Detalles Bibliográficos
Autores principales: Voorhees, Matthew A., Padilla, Susana L., Jamsransuren, Dulamjav, Koehler, Jeffrey W., Delp, Korey L., Adiyadorj, Dolgorkhand, Baasandagwa, Uyanga, Jigjav, Battsetseg, Olschner, Scott P., Minogue, Timothy D., Schoepp, Randal J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256378/
https://www.ncbi.nlm.nih.gov/pubmed/30457521
http://dx.doi.org/10.3201/eid2412.180175
_version_ 1783374133425340416
author Voorhees, Matthew A.
Padilla, Susana L.
Jamsransuren, Dulamjav
Koehler, Jeffrey W.
Delp, Korey L.
Adiyadorj, Dolgorkhand
Baasandagwa, Uyanga
Jigjav, Battsetseg
Olschner, Scott P.
Minogue, Timothy D.
Schoepp, Randal J.
author_facet Voorhees, Matthew A.
Padilla, Susana L.
Jamsransuren, Dulamjav
Koehler, Jeffrey W.
Delp, Korey L.
Adiyadorj, Dolgorkhand
Baasandagwa, Uyanga
Jigjav, Battsetseg
Olschner, Scott P.
Minogue, Timothy D.
Schoepp, Randal J.
author_sort Voorhees, Matthew A.
collection PubMed
description During 2013–2014, we collected 1,926 serum samples from humans and 4,583 ticks (Hyalomma asiaticum or Dermacentor nuttalli) in select regions of Mongolia to determine the risk for Crimean-Congo hemorrhagic fever virus (CCHFV) infection among humans in this country. Testing of human serum samples by ELISA demonstrated an overall CCHFV antibody prevalence of 1.4%; Bayankhongor Province had the highest prevalence, 2.63%. We pooled and analyzed tick specimens by real-time reverse transcription PCR; 1 CCHFV-positive H. asiaticum tick pool from Ömnögovi was identified. In phylogenetic analyses, the virus’s partial small segment clustered with CCHFV isolates from Central Asia, and the complete medium segment grouped with CCHFV isolates from Africa, Asia, and the Middle East. This study confirms CCHFV endemicity in Mongolia and provides information on risk for CCHFV infection. Further research is needed to better define the risk for CCHFV disease to improve risk mitigation, diagnostics, and surveillance.
format Online
Article
Text
id pubmed-6256378
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-62563782018-12-05 Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014 Voorhees, Matthew A. Padilla, Susana L. Jamsransuren, Dulamjav Koehler, Jeffrey W. Delp, Korey L. Adiyadorj, Dolgorkhand Baasandagwa, Uyanga Jigjav, Battsetseg Olschner, Scott P. Minogue, Timothy D. Schoepp, Randal J. Emerg Infect Dis Research During 2013–2014, we collected 1,926 serum samples from humans and 4,583 ticks (Hyalomma asiaticum or Dermacentor nuttalli) in select regions of Mongolia to determine the risk for Crimean-Congo hemorrhagic fever virus (CCHFV) infection among humans in this country. Testing of human serum samples by ELISA demonstrated an overall CCHFV antibody prevalence of 1.4%; Bayankhongor Province had the highest prevalence, 2.63%. We pooled and analyzed tick specimens by real-time reverse transcription PCR; 1 CCHFV-positive H. asiaticum tick pool from Ömnögovi was identified. In phylogenetic analyses, the virus’s partial small segment clustered with CCHFV isolates from Central Asia, and the complete medium segment grouped with CCHFV isolates from Africa, Asia, and the Middle East. This study confirms CCHFV endemicity in Mongolia and provides information on risk for CCHFV infection. Further research is needed to better define the risk for CCHFV disease to improve risk mitigation, diagnostics, and surveillance. Centers for Disease Control and Prevention 2018-12 /pmc/articles/PMC6256378/ /pubmed/30457521 http://dx.doi.org/10.3201/eid2412.180175 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Voorhees, Matthew A.
Padilla, Susana L.
Jamsransuren, Dulamjav
Koehler, Jeffrey W.
Delp, Korey L.
Adiyadorj, Dolgorkhand
Baasandagwa, Uyanga
Jigjav, Battsetseg
Olschner, Scott P.
Minogue, Timothy D.
Schoepp, Randal J.
Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014
title Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014
title_full Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014
title_fullStr Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014
title_full_unstemmed Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014
title_short Crimean-Congo Hemorrhagic Fever Virus, Mongolia, 2013–2014
title_sort crimean-congo hemorrhagic fever virus, mongolia, 2013–2014
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256378/
https://www.ncbi.nlm.nih.gov/pubmed/30457521
http://dx.doi.org/10.3201/eid2412.180175
work_keys_str_mv AT voorheesmatthewa crimeancongohemorrhagicfevervirusmongolia20132014
AT padillasusanal crimeancongohemorrhagicfevervirusmongolia20132014
AT jamsransurendulamjav crimeancongohemorrhagicfevervirusmongolia20132014
AT koehlerjeffreyw crimeancongohemorrhagicfevervirusmongolia20132014
AT delpkoreyl crimeancongohemorrhagicfevervirusmongolia20132014
AT adiyadorjdolgorkhand crimeancongohemorrhagicfevervirusmongolia20132014
AT baasandagwauyanga crimeancongohemorrhagicfevervirusmongolia20132014
AT jigjavbattsetseg crimeancongohemorrhagicfevervirusmongolia20132014
AT olschnerscottp crimeancongohemorrhagicfevervirusmongolia20132014
AT minoguetimothyd crimeancongohemorrhagicfevervirusmongolia20132014
AT schoepprandalj crimeancongohemorrhagicfevervirusmongolia20132014