Use of Next-Generation Sequencing for Diagnosis of West Nile Virus Infection in Patient Returning to Belgium from Hungary

An elderly patient in Belgium who became critically ill after returning from Hungary was tested for pathogens using routine diagnostic tests. All results were negative. However, using next-generation sequencing on a cultured respiratory sample, laboratorians detected a complete West Nile virus genom...

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Autores principales: Wollants, Elke, Smolders, David, Naesens, Reinout, Bruynseels, Peggy, Lagrou, Katrien, Matthijnssens, Jelle, Van Ranst, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256386/
https://www.ncbi.nlm.nih.gov/pubmed/30457549
http://dx.doi.org/10.3201/eid2412.180494
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author Wollants, Elke
Smolders, David
Naesens, Reinout
Bruynseels, Peggy
Lagrou, Katrien
Matthijnssens, Jelle
Van Ranst, Marc
author_facet Wollants, Elke
Smolders, David
Naesens, Reinout
Bruynseels, Peggy
Lagrou, Katrien
Matthijnssens, Jelle
Van Ranst, Marc
author_sort Wollants, Elke
collection PubMed
description An elderly patient in Belgium who became critically ill after returning from Hungary was tested for pathogens using routine diagnostic tests. All results were negative. However, using next-generation sequencing on a cultured respiratory sample, laboratorians detected a complete West Nile virus genome, similar to strains isolated in southeastern Europe.
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spelling pubmed-62563862018-12-05 Use of Next-Generation Sequencing for Diagnosis of West Nile Virus Infection in Patient Returning to Belgium from Hungary Wollants, Elke Smolders, David Naesens, Reinout Bruynseels, Peggy Lagrou, Katrien Matthijnssens, Jelle Van Ranst, Marc Emerg Infect Dis Research Letter An elderly patient in Belgium who became critically ill after returning from Hungary was tested for pathogens using routine diagnostic tests. All results were negative. However, using next-generation sequencing on a cultured respiratory sample, laboratorians detected a complete West Nile virus genome, similar to strains isolated in southeastern Europe. Centers for Disease Control and Prevention 2018-12 /pmc/articles/PMC6256386/ /pubmed/30457549 http://dx.doi.org/10.3201/eid2412.180494 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Wollants, Elke
Smolders, David
Naesens, Reinout
Bruynseels, Peggy
Lagrou, Katrien
Matthijnssens, Jelle
Van Ranst, Marc
Use of Next-Generation Sequencing for Diagnosis of West Nile Virus Infection in Patient Returning to Belgium from Hungary
title Use of Next-Generation Sequencing for Diagnosis of West Nile Virus Infection in Patient Returning to Belgium from Hungary
title_full Use of Next-Generation Sequencing for Diagnosis of West Nile Virus Infection in Patient Returning to Belgium from Hungary
title_fullStr Use of Next-Generation Sequencing for Diagnosis of West Nile Virus Infection in Patient Returning to Belgium from Hungary
title_full_unstemmed Use of Next-Generation Sequencing for Diagnosis of West Nile Virus Infection in Patient Returning to Belgium from Hungary
title_short Use of Next-Generation Sequencing for Diagnosis of West Nile Virus Infection in Patient Returning to Belgium from Hungary
title_sort use of next-generation sequencing for diagnosis of west nile virus infection in patient returning to belgium from hungary
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256386/
https://www.ncbi.nlm.nih.gov/pubmed/30457549
http://dx.doi.org/10.3201/eid2412.180494
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