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Survey of Ebola Viruses in Frugivorous and Insectivorous Bats in Guinea, Cameroon, and the Democratic Republic of the Congo, 2015–2017

To clarify the role of bats in the ecology of Ebola viruses, we assessed the prevalence of Ebola virus antibodies in a large-scale sample of bats collected during 2015–2017 from countries in Africa that have had previous Ebola outbreaks (Guinea, the Democratic Republic of the Congo) or are at high r...

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Autores principales: De Nys, Helene M., Kingebeni, Placide Mbala, Keita, Alpha K., Butel, Christelle, Thaurignac, Guillaume, Villabona-Arenas, Christian-Julian, Lemarcis, Thomas, Geraerts, Mare, Vidal, Nicole, Esteban, Amandine, Bourgarel, Mathieu, Roger, François, Leendertz, Fabian, Diallo, Ramadan, Ndimbo-Kumugo, Simon-Pierre, Nsio-Mbeta, Justus, Tagg, Nikki, Koivogui, Lamine, Toure, Abdoulaye, Delaporte, Eric, Ahuka-Mundeke, Steve, Tamfum, Jean-Jacques Muyembe, Mpoudi-Ngole, Eitel, Ayouba, Ahidjo, Peeters, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256401/
https://www.ncbi.nlm.nih.gov/pubmed/30307845
http://dx.doi.org/10.3201/eid2412.180740
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author De Nys, Helene M.
Kingebeni, Placide Mbala
Keita, Alpha K.
Butel, Christelle
Thaurignac, Guillaume
Villabona-Arenas, Christian-Julian
Lemarcis, Thomas
Geraerts, Mare
Vidal, Nicole
Esteban, Amandine
Bourgarel, Mathieu
Roger, François
Leendertz, Fabian
Diallo, Ramadan
Ndimbo-Kumugo, Simon-Pierre
Nsio-Mbeta, Justus
Tagg, Nikki
Koivogui, Lamine
Toure, Abdoulaye
Delaporte, Eric
Ahuka-Mundeke, Steve
Tamfum, Jean-Jacques Muyembe
Mpoudi-Ngole, Eitel
Ayouba, Ahidjo
Peeters, Martine
author_facet De Nys, Helene M.
Kingebeni, Placide Mbala
Keita, Alpha K.
Butel, Christelle
Thaurignac, Guillaume
Villabona-Arenas, Christian-Julian
Lemarcis, Thomas
Geraerts, Mare
Vidal, Nicole
Esteban, Amandine
Bourgarel, Mathieu
Roger, François
Leendertz, Fabian
Diallo, Ramadan
Ndimbo-Kumugo, Simon-Pierre
Nsio-Mbeta, Justus
Tagg, Nikki
Koivogui, Lamine
Toure, Abdoulaye
Delaporte, Eric
Ahuka-Mundeke, Steve
Tamfum, Jean-Jacques Muyembe
Mpoudi-Ngole, Eitel
Ayouba, Ahidjo
Peeters, Martine
author_sort De Nys, Helene M.
collection PubMed
description To clarify the role of bats in the ecology of Ebola viruses, we assessed the prevalence of Ebola virus antibodies in a large-scale sample of bats collected during 2015–2017 from countries in Africa that have had previous Ebola outbreaks (Guinea, the Democratic Republic of the Congo) or are at high risk for outbreaks (Cameroon). We analyzed 4,022 blood samples of bats from >12 frugivorous and 27 insectivorous species; 2–37 (0.05%–0.92%) bats were seropositive for Zaire and 0–30 (0%–0.75%) bats for Sudan Ebola viruses. We observed Ebola virus antibodies in 1 insectivorous bat genus and 6 frugivorous bat species. Certain bat species widespread across Africa had serologic evidence of Zaire and Sudan Ebola viruses. No viral RNA was detected in the subset of samples tested (n = 665). Ongoing surveillance of bats and other potential animal reservoirs are required to predict and prepare for future outbreaks.
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spelling pubmed-62564012018-12-05 Survey of Ebola Viruses in Frugivorous and Insectivorous Bats in Guinea, Cameroon, and the Democratic Republic of the Congo, 2015–2017 De Nys, Helene M. Kingebeni, Placide Mbala Keita, Alpha K. Butel, Christelle Thaurignac, Guillaume Villabona-Arenas, Christian-Julian Lemarcis, Thomas Geraerts, Mare Vidal, Nicole Esteban, Amandine Bourgarel, Mathieu Roger, François Leendertz, Fabian Diallo, Ramadan Ndimbo-Kumugo, Simon-Pierre Nsio-Mbeta, Justus Tagg, Nikki Koivogui, Lamine Toure, Abdoulaye Delaporte, Eric Ahuka-Mundeke, Steve Tamfum, Jean-Jacques Muyembe Mpoudi-Ngole, Eitel Ayouba, Ahidjo Peeters, Martine Emerg Infect Dis Research To clarify the role of bats in the ecology of Ebola viruses, we assessed the prevalence of Ebola virus antibodies in a large-scale sample of bats collected during 2015–2017 from countries in Africa that have had previous Ebola outbreaks (Guinea, the Democratic Republic of the Congo) or are at high risk for outbreaks (Cameroon). We analyzed 4,022 blood samples of bats from >12 frugivorous and 27 insectivorous species; 2–37 (0.05%–0.92%) bats were seropositive for Zaire and 0–30 (0%–0.75%) bats for Sudan Ebola viruses. We observed Ebola virus antibodies in 1 insectivorous bat genus and 6 frugivorous bat species. Certain bat species widespread across Africa had serologic evidence of Zaire and Sudan Ebola viruses. No viral RNA was detected in the subset of samples tested (n = 665). Ongoing surveillance of bats and other potential animal reservoirs are required to predict and prepare for future outbreaks. Centers for Disease Control and Prevention 2018-12 /pmc/articles/PMC6256401/ /pubmed/30307845 http://dx.doi.org/10.3201/eid2412.180740 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
De Nys, Helene M.
Kingebeni, Placide Mbala
Keita, Alpha K.
Butel, Christelle
Thaurignac, Guillaume
Villabona-Arenas, Christian-Julian
Lemarcis, Thomas
Geraerts, Mare
Vidal, Nicole
Esteban, Amandine
Bourgarel, Mathieu
Roger, François
Leendertz, Fabian
Diallo, Ramadan
Ndimbo-Kumugo, Simon-Pierre
Nsio-Mbeta, Justus
Tagg, Nikki
Koivogui, Lamine
Toure, Abdoulaye
Delaporte, Eric
Ahuka-Mundeke, Steve
Tamfum, Jean-Jacques Muyembe
Mpoudi-Ngole, Eitel
Ayouba, Ahidjo
Peeters, Martine
Survey of Ebola Viruses in Frugivorous and Insectivorous Bats in Guinea, Cameroon, and the Democratic Republic of the Congo, 2015–2017
title Survey of Ebola Viruses in Frugivorous and Insectivorous Bats in Guinea, Cameroon, and the Democratic Republic of the Congo, 2015–2017
title_full Survey of Ebola Viruses in Frugivorous and Insectivorous Bats in Guinea, Cameroon, and the Democratic Republic of the Congo, 2015–2017
title_fullStr Survey of Ebola Viruses in Frugivorous and Insectivorous Bats in Guinea, Cameroon, and the Democratic Republic of the Congo, 2015–2017
title_full_unstemmed Survey of Ebola Viruses in Frugivorous and Insectivorous Bats in Guinea, Cameroon, and the Democratic Republic of the Congo, 2015–2017
title_short Survey of Ebola Viruses in Frugivorous and Insectivorous Bats in Guinea, Cameroon, and the Democratic Republic of the Congo, 2015–2017
title_sort survey of ebola viruses in frugivorous and insectivorous bats in guinea, cameroon, and the democratic republic of the congo, 2015–2017
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256401/
https://www.ncbi.nlm.nih.gov/pubmed/30307845
http://dx.doi.org/10.3201/eid2412.180740
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