First Complete Genome Sequence of a Genotype A2, Subgroup 4 Small Ruminant Lentivirus

Genetic variation in the ovine TMEM154 gene associates with susceptibility to small ruminant lentivirus (SRLV) infection. We report here the first complete genome sequence for a genotype A2, subgroup 4 SRLV isolated from a Hampshire ewe with two copies of a TMEM154 frameshift mutation predicted to a...

Descripción completa

Detalles Bibliográficos
Autores principales: Workman, Aspen M., Clawson, Michael L., Heaton, Michael P., Dickey, Aaron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256481/
https://www.ncbi.nlm.nih.gov/pubmed/30533794
http://dx.doi.org/10.1128/MRA.01337-18
_version_ 1783374157540491264
author Workman, Aspen M.
Clawson, Michael L.
Heaton, Michael P.
Dickey, Aaron M.
author_facet Workman, Aspen M.
Clawson, Michael L.
Heaton, Michael P.
Dickey, Aaron M.
author_sort Workman, Aspen M.
collection PubMed
description Genetic variation in the ovine TMEM154 gene associates with susceptibility to small ruminant lentivirus (SRLV) infection. We report here the first complete genome sequence for a genotype A2, subgroup 4 SRLV isolated from a Hampshire ewe with two copies of a TMEM154 frameshift mutation predicted to abolish protein function.
format Online
Article
Text
id pubmed-6256481
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher American Society for Microbiology
record_format MEDLINE/PubMed
spelling pubmed-62564812018-12-07 First Complete Genome Sequence of a Genotype A2, Subgroup 4 Small Ruminant Lentivirus Workman, Aspen M. Clawson, Michael L. Heaton, Michael P. Dickey, Aaron M. Microbiol Resour Announc Genome Sequences Genetic variation in the ovine TMEM154 gene associates with susceptibility to small ruminant lentivirus (SRLV) infection. We report here the first complete genome sequence for a genotype A2, subgroup 4 SRLV isolated from a Hampshire ewe with two copies of a TMEM154 frameshift mutation predicted to abolish protein function. American Society for Microbiology 2018-11-15 /pmc/articles/PMC6256481/ /pubmed/30533794 http://dx.doi.org/10.1128/MRA.01337-18 Text en https://doi.org/10.1128/AuthorWarrantyLicense.v1 This is a work of the U.S. Government and is not subject to copyright protection in the United States. Foreign copyrights may apply.
spellingShingle Genome Sequences
Workman, Aspen M.
Clawson, Michael L.
Heaton, Michael P.
Dickey, Aaron M.
First Complete Genome Sequence of a Genotype A2, Subgroup 4 Small Ruminant Lentivirus
title First Complete Genome Sequence of a Genotype A2, Subgroup 4 Small Ruminant Lentivirus
title_full First Complete Genome Sequence of a Genotype A2, Subgroup 4 Small Ruminant Lentivirus
title_fullStr First Complete Genome Sequence of a Genotype A2, Subgroup 4 Small Ruminant Lentivirus
title_full_unstemmed First Complete Genome Sequence of a Genotype A2, Subgroup 4 Small Ruminant Lentivirus
title_short First Complete Genome Sequence of a Genotype A2, Subgroup 4 Small Ruminant Lentivirus
title_sort first complete genome sequence of a genotype a2, subgroup 4 small ruminant lentivirus
topic Genome Sequences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256481/
https://www.ncbi.nlm.nih.gov/pubmed/30533794
http://dx.doi.org/10.1128/MRA.01337-18
work_keys_str_mv AT workmanaspenm firstcompletegenomesequenceofagenotypea2subgroup4smallruminantlentivirus
AT clawsonmichaell firstcompletegenomesequenceofagenotypea2subgroup4smallruminantlentivirus
AT heatonmichaelp firstcompletegenomesequenceofagenotypea2subgroup4smallruminantlentivirus
AT dickeyaaronm firstcompletegenomesequenceofagenotypea2subgroup4smallruminantlentivirus

Ejemplares similares