Artificial Immune System–Negative Selection Classification Algorithm (NSCA) for Four Class Electroencephalogram (EEG) Signals

Artificial immune systems (AIS) are intelligent algorithms derived from the principles inspired by the human immune system. In this study, electroencephalography (EEG) signals for four distinct motor movements of human limbs are detected and classified using a negative selection classification algorithm (NSCA). For this study, a widely studied open source EEG signal database (BCI IV–Graz dataset 2a, comprising nine subjects) has been used. Mel frequency cepstral coefficients (MFCCs) are extracted as selected features from recorded EEG signals. Dimensionality reduction of data is carried out by applying two hidden layered stacked auto-encoder. Genetic algorithm (GA) optimized detectors (artificial lymphocytes) are trained using negative selection algorithm (NSA) for detection and classification of four motor movements. The trained detectors consist of four sets of detectors, each set is trained for detection and classification of one of the four movements from the other three movements. The optimized radius of detector is small enough not to mis-detect the sample. Euclidean distance of each detector with every training dataset sample is taken and compared with the optimized radius of the detector as a nonself detector. Our proposed approach achieved a mean classification accuracy of 86.39% for limb movements over nine subjects with a maximum individual subject classification accuracy of 97.5% for subject number eight.