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Pentoxifylline Alone or in Combination with Gentamicin or Vancomycin Inhibits Live Microbe-Induced Proinflammatory Cytokine Production in Human Cord Blood and Cord Blood Monocytes In Vitro

Neonatal sepsis and its accompanying inflammatory response contribute to substantial morbidity and mortality. Pentoxifylline (PTX), a phosphodiesterase inhibitor which suppresses transcription and production of proinflammatory cytokines, is a candidate adjunctive therapy for newborn sepsis. We hypot...

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Detalles Bibliográficos
Autores principales:	Speer, Esther M., Diago-Navarro, Elizabeth, Ozog, Lukasz S., Dowling, David J., Hou, Wei, Raheel, Mahnoor, Fries, Bettina C., Levy, Ofer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Biologic Response Modifiers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256750/ https://www.ncbi.nlm.nih.gov/pubmed/30275087 http://dx.doi.org/10.1128/AAC.01462-18

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