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Rare case of idiopathic sclerosing cholangitis, which was difficult to distinguish from cholangiocarcinoma: A case report
It is often difficult to correctly diagnose patients who present with dilation of the bile duct. Cholangiocarcinoma, primary sclerosing cholangitis (PSC) and immunoglobulin (Ig)G4-related sclerosing cholangitis must be considered as potential diagnoses for these cases. The current study presents a 7...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256851/ https://www.ncbi.nlm.nih.gov/pubmed/30546416 http://dx.doi.org/10.3892/etm.2018.6832 |
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author | Shichi, Shunsuke Einama, Takahiro Suzuki, Mayu Matsui, Hiroki Kanazawa, Ryo Shibuya, Kazuaki Suzuki, Takashi Matsuzawa, Fumihiko Nakachi, Kohei Hashimoto, Taku Kondo, Nobuo Abe, Hironori Taketomi, Akinobu |
author_facet | Shichi, Shunsuke Einama, Takahiro Suzuki, Mayu Matsui, Hiroki Kanazawa, Ryo Shibuya, Kazuaki Suzuki, Takashi Matsuzawa, Fumihiko Nakachi, Kohei Hashimoto, Taku Kondo, Nobuo Abe, Hironori Taketomi, Akinobu |
author_sort | Shichi, Shunsuke |
collection | PubMed |
description | It is often difficult to correctly diagnose patients who present with dilation of the bile duct. Cholangiocarcinoma, primary sclerosing cholangitis (PSC) and immunoglobulin (Ig)G4-related sclerosing cholangitis must be considered as potential diagnoses for these cases. The current study presents a 73-year-old female patient who presented with a high fever and abdominal pain. Contrast-enhanced computed tomography and magnetic resonance cholangiopancreatography revealed stenosis and dilation of the intrahepatic bile duct without solid components. It was suspected that the patient had intrahepatic cholangiocarcinoma. A left liver lobectomy, cholecystectomy and distal gastrectomy combined with a D2 lymph node dissection were performed. A pathological examination of the liver revealed increased fibrosis in the stroma, irregular bile duct dilation and clusters of inflamed lymph cells. No carcinoma or IgG4-positive plasma cells were observed and the typical findings of PSC were not detected. Based on these clinical and pathological results, the diagnosis was idiopathic sclerosing cholangitis, which is particularly rare. It is often difficult to preoperatively differentiate between cholangiocarcinoma and benign bile duct stenosis. |
format | Online Article Text |
id | pubmed-6256851 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-62568512018-12-13 Rare case of idiopathic sclerosing cholangitis, which was difficult to distinguish from cholangiocarcinoma: A case report Shichi, Shunsuke Einama, Takahiro Suzuki, Mayu Matsui, Hiroki Kanazawa, Ryo Shibuya, Kazuaki Suzuki, Takashi Matsuzawa, Fumihiko Nakachi, Kohei Hashimoto, Taku Kondo, Nobuo Abe, Hironori Taketomi, Akinobu Exp Ther Med Articles It is often difficult to correctly diagnose patients who present with dilation of the bile duct. Cholangiocarcinoma, primary sclerosing cholangitis (PSC) and immunoglobulin (Ig)G4-related sclerosing cholangitis must be considered as potential diagnoses for these cases. The current study presents a 73-year-old female patient who presented with a high fever and abdominal pain. Contrast-enhanced computed tomography and magnetic resonance cholangiopancreatography revealed stenosis and dilation of the intrahepatic bile duct without solid components. It was suspected that the patient had intrahepatic cholangiocarcinoma. A left liver lobectomy, cholecystectomy and distal gastrectomy combined with a D2 lymph node dissection were performed. A pathological examination of the liver revealed increased fibrosis in the stroma, irregular bile duct dilation and clusters of inflamed lymph cells. No carcinoma or IgG4-positive plasma cells were observed and the typical findings of PSC were not detected. Based on these clinical and pathological results, the diagnosis was idiopathic sclerosing cholangitis, which is particularly rare. It is often difficult to preoperatively differentiate between cholangiocarcinoma and benign bile duct stenosis. D.A. Spandidos 2018-12 2018-10-05 /pmc/articles/PMC6256851/ /pubmed/30546416 http://dx.doi.org/10.3892/etm.2018.6832 Text en Copyright: © Shichi et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Shichi, Shunsuke Einama, Takahiro Suzuki, Mayu Matsui, Hiroki Kanazawa, Ryo Shibuya, Kazuaki Suzuki, Takashi Matsuzawa, Fumihiko Nakachi, Kohei Hashimoto, Taku Kondo, Nobuo Abe, Hironori Taketomi, Akinobu Rare case of idiopathic sclerosing cholangitis, which was difficult to distinguish from cholangiocarcinoma: A case report |
title | Rare case of idiopathic sclerosing cholangitis, which was difficult to distinguish from cholangiocarcinoma: A case report |
title_full | Rare case of idiopathic sclerosing cholangitis, which was difficult to distinguish from cholangiocarcinoma: A case report |
title_fullStr | Rare case of idiopathic sclerosing cholangitis, which was difficult to distinguish from cholangiocarcinoma: A case report |
title_full_unstemmed | Rare case of idiopathic sclerosing cholangitis, which was difficult to distinguish from cholangiocarcinoma: A case report |
title_short | Rare case of idiopathic sclerosing cholangitis, which was difficult to distinguish from cholangiocarcinoma: A case report |
title_sort | rare case of idiopathic sclerosing cholangitis, which was difficult to distinguish from cholangiocarcinoma: a case report |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256851/ https://www.ncbi.nlm.nih.gov/pubmed/30546416 http://dx.doi.org/10.3892/etm.2018.6832 |
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