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Neuroprotective role of dexmedetomidine pretreatment in cerebral ischemia injury via ADRA2A-mediated phosphorylation of ERK1/2 in adult rats

Neuroprotective effects of dexmedetomidine (Dex) have been reported in various models of brain injury. However, to our knowledge, the neuroprotective mechanism of Dex pretreatment in rats remains unknown. The aim of the present study was to detect the expression of the α2A adrenergic receptor (ADRA2...

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Detalles Bibliográficos
Autores principales: Shi, Yanyan, Peng, Xiao-Hong, Li, Xia, Luo, Gao-Ping, Wu, Ming-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256861/
https://www.ncbi.nlm.nih.gov/pubmed/30546415
http://dx.doi.org/10.3892/etm.2018.6878