CXCR4 Antagonist Reduced the Incidence of Acute Rejection and Controlled Cardiac Allograft Vasculopathy in a Swine Heart Transplant Model Receiving a Mycophenolate-based Immunosuppressive Regimen

BACKGROUND: CXC motif chemokine receptor 4 (CXCR4) blockade is pursued as an alternative to mesenchymal stem cell treatment in transplantation based on our previous report that burixafor, through CXCR4 antagonism, mobilizes immunomodulatory mesenchymal stem cells. Here, we explored the efficacy of c...

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Detalles Bibliográficos
Autores principales: Hsu, Wan-Tseng, Lin, Cheng-Hsin, Jui, Hsiang-Yiang, Tseng, Ya-Hsuan, Shun, Chia-Tung, Hsu, Ming-Chu, Wu, Kenneth Kun-Yu, Lee, Chii-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Original Basic Science—General
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257103/
https://www.ncbi.nlm.nih.gov/pubmed/30095739
http://dx.doi.org/10.1097/TP.0000000000002404

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