Caloxanthones O and P: Two New Prenylated Xanthones from Calophyllum inophyllum

Chemical investigation of the EtOH extract of the twigs of Calophyllum inophyllum collected in Hainan Province of China resulted in the isolation of two new prenylated xanthones, caloxanthone O (1) and caloxanthone P (2). Their structures were elucidated by a study of their physical and spectral dat...

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Detalles Bibliográficos
Autores principales: Dai, Hao-Fu, Zeng, Yan-Bo, Xiao, Qi, Han, Zhuang, Zhao, You-Xing, Mei, Wen-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257128/
https://www.ncbi.nlm.nih.gov/pubmed/20335930
http://dx.doi.org/10.3390/molecules15020606
Descripción
Sumario:Chemical investigation of the EtOH extract of the twigs of Calophyllum inophyllum collected in Hainan Province of China resulted in the isolation of two new prenylated xanthones, caloxanthone O (1) and caloxanthone P (2). Their structures were elucidated by a study of their physical and spectral data. Compound 1 exhibited cytotoxicity against human gastric cancer cell line (SGC-7901), with an IC(50) value of 22.4 μg mL(−1).

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