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Effects of femtosecond laser-assisted cataract surgery on dry eye

The aim of this study was to investigate the effect of femtosecond laser-assisted cataract surgery (FLACS) on tear film and ocular surface function. Patients with age-related cataract who underwent phacoemulsification (phaco) in Air Force Aviation Medicine Research Institute Affiliation Hospital fro...

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Autores principales: Shao, Dewang, Zhu, Xiaoquan, Sun, Wei, Cheng, Peng, Chen, Wei, Wang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257160/
https://www.ncbi.nlm.nih.gov/pubmed/30542462
http://dx.doi.org/10.3892/etm.2018.6862
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author Shao, Dewang
Zhu, Xiaoquan
Sun, Wei
Cheng, Peng
Chen, Wei
Wang, Hua
author_facet Shao, Dewang
Zhu, Xiaoquan
Sun, Wei
Cheng, Peng
Chen, Wei
Wang, Hua
author_sort Shao, Dewang
collection PubMed
description The aim of this study was to investigate the effect of femtosecond laser-assisted cataract surgery (FLACS) on tear film and ocular surface function. Patients with age-related cataract who underwent phacoemulsification (phaco) in Air Force Aviation Medicine Research Institute Affiliation Hospital from January 2016 to December 2016 were randomly divided into two groups. Patients in experimental group (n=123, 150 eyes) received FLACS, while patients in phaco group (n=110, 150 eyes) underwent conventional coaxial micro-incision phaco and were implanted with foldable intraocular lens (IOL). Our results showed that there were no statistically significant differences in general conditions between the two groups. Ocular surface disease index (OSDI) and corneal fluorescein staining (CFS) scores of patients in both groups after operation were significantly increased compared with those before operation, but breakup time (BUT) and Schirmer's I test scores decreased significantly at 1 week after operation compared with those before operation and basically returned to preoperative baseline levels at 3 months after operation. CFS scores and OSDI in the FLACS group at 1 day and 1 week after operation were increased more significantly than those in the phaco group, but there were no statistically significant differences at 3 months after operation. The above results showed that the effect on ocular surface function in the FLACS group after operation was greater than that in the phaco group, and the dry eye symptoms in the FLACS group were more obvious after operation. Both FLACS and conventional phaco have certain effects on the ocular surface function of patients, and there are statistically significant differences only in the early stage. FLACS has greater effects on CFS and dry eye symptoms.
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spelling pubmed-62571602018-12-12 Effects of femtosecond laser-assisted cataract surgery on dry eye Shao, Dewang Zhu, Xiaoquan Sun, Wei Cheng, Peng Chen, Wei Wang, Hua Exp Ther Med Articles The aim of this study was to investigate the effect of femtosecond laser-assisted cataract surgery (FLACS) on tear film and ocular surface function. Patients with age-related cataract who underwent phacoemulsification (phaco) in Air Force Aviation Medicine Research Institute Affiliation Hospital from January 2016 to December 2016 were randomly divided into two groups. Patients in experimental group (n=123, 150 eyes) received FLACS, while patients in phaco group (n=110, 150 eyes) underwent conventional coaxial micro-incision phaco and were implanted with foldable intraocular lens (IOL). Our results showed that there were no statistically significant differences in general conditions between the two groups. Ocular surface disease index (OSDI) and corneal fluorescein staining (CFS) scores of patients in both groups after operation were significantly increased compared with those before operation, but breakup time (BUT) and Schirmer's I test scores decreased significantly at 1 week after operation compared with those before operation and basically returned to preoperative baseline levels at 3 months after operation. CFS scores and OSDI in the FLACS group at 1 day and 1 week after operation were increased more significantly than those in the phaco group, but there were no statistically significant differences at 3 months after operation. The above results showed that the effect on ocular surface function in the FLACS group after operation was greater than that in the phaco group, and the dry eye symptoms in the FLACS group were more obvious after operation. Both FLACS and conventional phaco have certain effects on the ocular surface function of patients, and there are statistically significant differences only in the early stage. FLACS has greater effects on CFS and dry eye symptoms. D.A. Spandidos 2018-12 2018-10-15 /pmc/articles/PMC6257160/ /pubmed/30542462 http://dx.doi.org/10.3892/etm.2018.6862 Text en Copyright: © Shao et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Shao, Dewang
Zhu, Xiaoquan
Sun, Wei
Cheng, Peng
Chen, Wei
Wang, Hua
Effects of femtosecond laser-assisted cataract surgery on dry eye
title Effects of femtosecond laser-assisted cataract surgery on dry eye
title_full Effects of femtosecond laser-assisted cataract surgery on dry eye
title_fullStr Effects of femtosecond laser-assisted cataract surgery on dry eye
title_full_unstemmed Effects of femtosecond laser-assisted cataract surgery on dry eye
title_short Effects of femtosecond laser-assisted cataract surgery on dry eye
title_sort effects of femtosecond laser-assisted cataract surgery on dry eye
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257160/
https://www.ncbi.nlm.nih.gov/pubmed/30542462
http://dx.doi.org/10.3892/etm.2018.6862
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