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Vitamins and Prostate Cancer Risk

Prostate cancer (PC) is the second most common cancer in men worldwide. Its prevention and treatment remain a challenge to clinicians. Here we review the relationship of vitamins to PC risk. Many vitamins and related chemicals, including vitamin A, retinoids, several B vitamins, vitamin C, vitamin D...

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Autores principales: Donkena, Krishna Vanaja, Karnes, R. Jeffrey, Young, Charles Y.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257189/
https://www.ncbi.nlm.nih.gov/pubmed/20336012
http://dx.doi.org/10.3390/molecules15031762
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author Donkena, Krishna Vanaja
Karnes, R. Jeffrey
Young, Charles Y.F.
author_facet Donkena, Krishna Vanaja
Karnes, R. Jeffrey
Young, Charles Y.F.
author_sort Donkena, Krishna Vanaja
collection PubMed
description Prostate cancer (PC) is the second most common cancer in men worldwide. Its prevention and treatment remain a challenge to clinicians. Here we review the relationship of vitamins to PC risk. Many vitamins and related chemicals, including vitamin A, retinoids, several B vitamins, vitamin C, vitamin D and vitamin E have shown their anti-cancer activities as anti-oxidants, activators of transcription factors or factors influencing epigenetic events. Although laboratory tests including the use of animal models showed these vitamins may have anti-PC properties, whether they can effectively prevent the development and/or progression of PC in humans remains to be intensively studied subjects. This review will provide up-to-date information regarding the recent outcomes of laboratory, epidemiology and/or clinical trials on the effects of vitamins on PC prevention and/or treatment.
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spelling pubmed-62571892018-12-04 Vitamins and Prostate Cancer Risk Donkena, Krishna Vanaja Karnes, R. Jeffrey Young, Charles Y.F. Molecules Review Prostate cancer (PC) is the second most common cancer in men worldwide. Its prevention and treatment remain a challenge to clinicians. Here we review the relationship of vitamins to PC risk. Many vitamins and related chemicals, including vitamin A, retinoids, several B vitamins, vitamin C, vitamin D and vitamin E have shown their anti-cancer activities as anti-oxidants, activators of transcription factors or factors influencing epigenetic events. Although laboratory tests including the use of animal models showed these vitamins may have anti-PC properties, whether they can effectively prevent the development and/or progression of PC in humans remains to be intensively studied subjects. This review will provide up-to-date information regarding the recent outcomes of laboratory, epidemiology and/or clinical trials on the effects of vitamins on PC prevention and/or treatment. Molecular Diversity Preservation International 2010-03-12 /pmc/articles/PMC6257189/ /pubmed/20336012 http://dx.doi.org/10.3390/molecules15031762 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Donkena, Krishna Vanaja
Karnes, R. Jeffrey
Young, Charles Y.F.
Vitamins and Prostate Cancer Risk
title Vitamins and Prostate Cancer Risk
title_full Vitamins and Prostate Cancer Risk
title_fullStr Vitamins and Prostate Cancer Risk
title_full_unstemmed Vitamins and Prostate Cancer Risk
title_short Vitamins and Prostate Cancer Risk
title_sort vitamins and prostate cancer risk
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257189/
https://www.ncbi.nlm.nih.gov/pubmed/20336012
http://dx.doi.org/10.3390/molecules15031762
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