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Vitamins and Prostate Cancer Risk
Prostate cancer (PC) is the second most common cancer in men worldwide. Its prevention and treatment remain a challenge to clinicians. Here we review the relationship of vitamins to PC risk. Many vitamins and related chemicals, including vitamin A, retinoids, several B vitamins, vitamin C, vitamin D...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257189/ https://www.ncbi.nlm.nih.gov/pubmed/20336012 http://dx.doi.org/10.3390/molecules15031762 |
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author | Donkena, Krishna Vanaja Karnes, R. Jeffrey Young, Charles Y.F. |
author_facet | Donkena, Krishna Vanaja Karnes, R. Jeffrey Young, Charles Y.F. |
author_sort | Donkena, Krishna Vanaja |
collection | PubMed |
description | Prostate cancer (PC) is the second most common cancer in men worldwide. Its prevention and treatment remain a challenge to clinicians. Here we review the relationship of vitamins to PC risk. Many vitamins and related chemicals, including vitamin A, retinoids, several B vitamins, vitamin C, vitamin D and vitamin E have shown their anti-cancer activities as anti-oxidants, activators of transcription factors or factors influencing epigenetic events. Although laboratory tests including the use of animal models showed these vitamins may have anti-PC properties, whether they can effectively prevent the development and/or progression of PC in humans remains to be intensively studied subjects. This review will provide up-to-date information regarding the recent outcomes of laboratory, epidemiology and/or clinical trials on the effects of vitamins on PC prevention and/or treatment. |
format | Online Article Text |
id | pubmed-6257189 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Molecular Diversity Preservation International |
record_format | MEDLINE/PubMed |
spelling | pubmed-62571892018-12-04 Vitamins and Prostate Cancer Risk Donkena, Krishna Vanaja Karnes, R. Jeffrey Young, Charles Y.F. Molecules Review Prostate cancer (PC) is the second most common cancer in men worldwide. Its prevention and treatment remain a challenge to clinicians. Here we review the relationship of vitamins to PC risk. Many vitamins and related chemicals, including vitamin A, retinoids, several B vitamins, vitamin C, vitamin D and vitamin E have shown their anti-cancer activities as anti-oxidants, activators of transcription factors or factors influencing epigenetic events. Although laboratory tests including the use of animal models showed these vitamins may have anti-PC properties, whether they can effectively prevent the development and/or progression of PC in humans remains to be intensively studied subjects. This review will provide up-to-date information regarding the recent outcomes of laboratory, epidemiology and/or clinical trials on the effects of vitamins on PC prevention and/or treatment. Molecular Diversity Preservation International 2010-03-12 /pmc/articles/PMC6257189/ /pubmed/20336012 http://dx.doi.org/10.3390/molecules15031762 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Donkena, Krishna Vanaja Karnes, R. Jeffrey Young, Charles Y.F. Vitamins and Prostate Cancer Risk |
title | Vitamins and Prostate Cancer Risk |
title_full | Vitamins and Prostate Cancer Risk |
title_fullStr | Vitamins and Prostate Cancer Risk |
title_full_unstemmed | Vitamins and Prostate Cancer Risk |
title_short | Vitamins and Prostate Cancer Risk |
title_sort | vitamins and prostate cancer risk |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257189/ https://www.ncbi.nlm.nih.gov/pubmed/20336012 http://dx.doi.org/10.3390/molecules15031762 |
work_keys_str_mv | AT donkenakrishnavanaja vitaminsandprostatecancerrisk AT karnesrjeffrey vitaminsandprostatecancerrisk AT youngcharlesyf vitaminsandprostatecancerrisk |