Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents

A variety of novel bicyclic and tricyclic pyrimidine derivatives was obtained via reaction of 6-amino-2-thioxo-1H-pyrimidine-4-one (1) with a different reagents. The antimicrobial and anti-inflammatory activities of some of the synthesized compounds were tested.

Detalles Bibliográficos
Autores principales: Mohamed, Mosaad S., Awad, Samir M., Sayed, Amira Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257238/
https://www.ncbi.nlm.nih.gov/pubmed/20336018
http://dx.doi.org/10.3390/molecules15031882
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author Mohamed, Mosaad S.
Awad, Samir M.
Sayed, Amira Ibrahim
author_facet Mohamed, Mosaad S.
Awad, Samir M.
Sayed, Amira Ibrahim
author_sort Mohamed, Mosaad S.
collection PubMed
description A variety of novel bicyclic and tricyclic pyrimidine derivatives was obtained via reaction of 6-amino-2-thioxo-1H-pyrimidine-4-one (1) with a different reagents. The antimicrobial and anti-inflammatory activities of some of the synthesized compounds were tested.
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spelling pubmed-62572382018-12-04 Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents Mohamed, Mosaad S. Awad, Samir M. Sayed, Amira Ibrahim Molecules Article A variety of novel bicyclic and tricyclic pyrimidine derivatives was obtained via reaction of 6-amino-2-thioxo-1H-pyrimidine-4-one (1) with a different reagents. The antimicrobial and anti-inflammatory activities of some of the synthesized compounds were tested. Molecular Diversity Preservation International 2010-03-15 /pmc/articles/PMC6257238/ /pubmed/20336018 http://dx.doi.org/10.3390/molecules15031882 Text en © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Mohamed, Mosaad S.
Awad, Samir M.
Sayed, Amira Ibrahim
Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents
title Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents
title_full Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents
title_fullStr Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents
title_full_unstemmed Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents
title_short Synthesis of Certain Pyrimidine Derivatives as Antimicrobial Agents and Anti-Inflammatory Agents
title_sort synthesis of certain pyrimidine derivatives as antimicrobial agents and anti-inflammatory agents
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257238/
https://www.ncbi.nlm.nih.gov/pubmed/20336018
http://dx.doi.org/10.3390/molecules15031882
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