Organocatalytic Michael Addition of 1,3-Dicarbonyl Indane Compounds to Nitrostyrenes

To map out the efficient organocatalyst requirements in the Michael addition of 1,3-dicarbonyl indane compounds to nitrostyrenes, a dozen different amino organocatalysts containing a p-toluenesulfonyl group (Ts) have been evaluated; excellent enantio-selectivities (up to er 92:8) were obtained with...

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Autores principales: Jiang, Zhen-Yu, Yang, Hua-Meng, Ju, Ya-Dong, Li, Li, Luo, Meng-Xian, Lai, Guo-Qiao, Jiang, Jian-Xiong, Xu, Li-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257257/
https://www.ncbi.nlm.nih.gov/pubmed/20428063
http://dx.doi.org/10.3390/molecules15042551
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author Jiang, Zhen-Yu
Yang, Hua-Meng
Ju, Ya-Dong
Li, Li
Luo, Meng-Xian
Lai, Guo-Qiao
Jiang, Jian-Xiong
Xu, Li-Wen
author_facet Jiang, Zhen-Yu
Yang, Hua-Meng
Ju, Ya-Dong
Li, Li
Luo, Meng-Xian
Lai, Guo-Qiao
Jiang, Jian-Xiong
Xu, Li-Wen
author_sort Jiang, Zhen-Yu
collection PubMed
description To map out the efficient organocatalyst requirements in the Michael addition of 1,3-dicarbonyl indane compounds to nitrostyrenes, a dozen different amino organocatalysts containing a p-toluenesulfonyl group (Ts) have been evaluated; excellent enantio-selectivities (up to er 92:8) were obtained with a primary amine-based Ts-DPEN catalyst and a plausible catalytic reaction mechanism was proposed on the basis of the experimental results.
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spelling pubmed-62572572018-11-30 Organocatalytic Michael Addition of 1,3-Dicarbonyl Indane Compounds to Nitrostyrenes Jiang, Zhen-Yu Yang, Hua-Meng Ju, Ya-Dong Li, Li Luo, Meng-Xian Lai, Guo-Qiao Jiang, Jian-Xiong Xu, Li-Wen Molecules Article To map out the efficient organocatalyst requirements in the Michael addition of 1,3-dicarbonyl indane compounds to nitrostyrenes, a dozen different amino organocatalysts containing a p-toluenesulfonyl group (Ts) have been evaluated; excellent enantio-selectivities (up to er 92:8) were obtained with a primary amine-based Ts-DPEN catalyst and a plausible catalytic reaction mechanism was proposed on the basis of the experimental results. Molecular Diversity Preservation International 2010-04-12 /pmc/articles/PMC6257257/ /pubmed/20428063 http://dx.doi.org/10.3390/molecules15042551 Text en © 2010 by the authors; http://creativecommons.org/licenses/by/3.0/ licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Jiang, Zhen-Yu
Yang, Hua-Meng
Ju, Ya-Dong
Li, Li
Luo, Meng-Xian
Lai, Guo-Qiao
Jiang, Jian-Xiong
Xu, Li-Wen
Organocatalytic Michael Addition of 1,3-Dicarbonyl Indane Compounds to Nitrostyrenes
title Organocatalytic Michael Addition of 1,3-Dicarbonyl Indane Compounds to Nitrostyrenes
title_full Organocatalytic Michael Addition of 1,3-Dicarbonyl Indane Compounds to Nitrostyrenes
title_fullStr Organocatalytic Michael Addition of 1,3-Dicarbonyl Indane Compounds to Nitrostyrenes
title_full_unstemmed Organocatalytic Michael Addition of 1,3-Dicarbonyl Indane Compounds to Nitrostyrenes
title_short Organocatalytic Michael Addition of 1,3-Dicarbonyl Indane Compounds to Nitrostyrenes
title_sort organocatalytic michael addition of 1,3-dicarbonyl indane compounds to nitrostyrenes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257257/
https://www.ncbi.nlm.nih.gov/pubmed/20428063
http://dx.doi.org/10.3390/molecules15042551
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