The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity

This review is an overview of the last ten years’ use of the Mizoroki–Heck coupling applied to 1,2- and 1,3-dienes. Since both these systems form π-allyl palladium intermediates in Pd(0) coupling, they show particular chemical behavior. Many examples of 1,2-dienes Heck reactions are presented. 1,2-D...

Descripción completa

Detalles Bibliográficos
Autores principales: Deagostino, Annamaria, Prandi, Cristina, Tabasso, Silvia, Venturello, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257322/
https://www.ncbi.nlm.nih.gov/pubmed/20428072
http://dx.doi.org/10.3390/molecules15042667
_version_ 1783374299763048448
author Deagostino, Annamaria
Prandi, Cristina
Tabasso, Silvia
Venturello, Paolo
author_facet Deagostino, Annamaria
Prandi, Cristina
Tabasso, Silvia
Venturello, Paolo
author_sort Deagostino, Annamaria
collection PubMed
description This review is an overview of the last ten years’ use of the Mizoroki–Heck coupling applied to 1,2- and 1,3-dienes. Since both these systems form π-allyl palladium intermediates in Pd(0) coupling, they show particular chemical behavior. Many examples of 1,2-dienes Heck reactions are presented. 1,2-Dienes are important substrates because of their high reactivity that makes them useful building blocks for the synthesis of biologically relevant structures.
format Online
Article
Text
id pubmed-6257322
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Molecular Diversity Preservation International
record_format MEDLINE/PubMed
spelling pubmed-62573222018-11-30 The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity Deagostino, Annamaria Prandi, Cristina Tabasso, Silvia Venturello, Paolo Molecules Review This review is an overview of the last ten years’ use of the Mizoroki–Heck coupling applied to 1,2- and 1,3-dienes. Since both these systems form π-allyl palladium intermediates in Pd(0) coupling, they show particular chemical behavior. Many examples of 1,2-dienes Heck reactions are presented. 1,2-Dienes are important substrates because of their high reactivity that makes them useful building blocks for the synthesis of biologically relevant structures. Molecular Diversity Preservation International 2010-04-13 /pmc/articles/PMC6257322/ /pubmed/20428072 http://dx.doi.org/10.3390/molecules15042667 Text en © 2010 by the authors; http://creativecommons.org/licenses/by/3.0/ licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Deagostino, Annamaria
Prandi, Cristina
Tabasso, Silvia
Venturello, Paolo
The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity
title The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity
title_full The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity
title_fullStr The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity
title_full_unstemmed The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity
title_short The Heck Reaction Applied to 1,3- and 1,2-Unsaturated Derivatives, a Way towards Molecular Complexity
title_sort heck reaction applied to 1,3- and 1,2-unsaturated derivatives, a way towards molecular complexity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257322/
https://www.ncbi.nlm.nih.gov/pubmed/20428072
http://dx.doi.org/10.3390/molecules15042667
work_keys_str_mv AT deagostinoannamaria theheckreactionappliedto13and12unsaturatedderivativesawaytowardsmolecularcomplexity
AT prandicristina theheckreactionappliedto13and12unsaturatedderivativesawaytowardsmolecularcomplexity
AT tabassosilvia theheckreactionappliedto13and12unsaturatedderivativesawaytowardsmolecularcomplexity
AT venturellopaolo theheckreactionappliedto13and12unsaturatedderivativesawaytowardsmolecularcomplexity
AT deagostinoannamaria heckreactionappliedto13and12unsaturatedderivativesawaytowardsmolecularcomplexity
AT prandicristina heckreactionappliedto13and12unsaturatedderivativesawaytowardsmolecularcomplexity
AT tabassosilvia heckreactionappliedto13and12unsaturatedderivativesawaytowardsmolecularcomplexity
AT venturellopaolo heckreactionappliedto13and12unsaturatedderivativesawaytowardsmolecularcomplexity

Ejemplares similares