Stereodynamic Investigation of Labile Stereogenic Centres in Dihydroartemisinin

Since its identification in the early 1970s, artemisinin, as well as semi-synthetic derivatives and synthetic trioxanes, have been used in malaria therapy. Reduction of artemisinin by NaBH(4) produced dihydroartemisinin (DHA), and yielded a new stereochemically labile centre at C-10, which, in turn,...

Descripción completa

Detalles Bibliográficos
Autores principales: D’Acquarica, Ilaria, Gasparrini, Francesco, Kotoni, Dorina, Pierini, Marco, Villani, Claudio, Cabri, Walter, Mattia, Michela Di, Giorgi, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257325/
https://www.ncbi.nlm.nih.gov/pubmed/20335983
http://dx.doi.org/10.3390/molecules15031309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257325/
https://www.ncbi.nlm.nih.gov/pubmed/20335983
http://dx.doi.org/10.3390/molecules15031309

Ejemplares similares