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Ribozyme-Mediated Inhibition of 801-bp Deletion-Mutant Epidermal Growth Factor Receptor mRNA Expression in Glioblastoma Multiforme
The epidermal growth factor receptor (HER1/EGFR) is known to be disregulated in a large subgroup of glioblastoma multiforme cases. Disregulation of HER1/EGFR is related to malignant transformation and tumor growth in various human cancers, including malignant glioma. One mechanism that may lead to d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257566/ https://www.ncbi.nlm.nih.gov/pubmed/20657384 http://dx.doi.org/10.3390/molecules15074670 |