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Pharmaceutical Composition of Valsartan: β-Cyclodextrin: Physico–Chemical and Characterization Anti-Hypertensive Evaluation
Valsartan, a water-insoluble drug, is mainly used in the treatment of hypertension albeit with reduced oral bioavailability. The aim of work was to develop a valsartan:β-cyclodextrin (VAL:β-CD) pharmaceutical composition in order to improve its water solubility and bioavailability. The VAL:β-CD comp...
Autores principales: | Eduardo de Matos Jensen, Carlos, dos Santos, Robson Augusto Souza, Denadai, Angelo Márcio Leite, Santos, Cynthia Fernandes Ferreira, Braga, Aline Nardoni Gonçalves, Sinisterra, Rubén Dario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257619/ https://www.ncbi.nlm.nih.gov/pubmed/20657427 http://dx.doi.org/10.3390/molecules15064067 |
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