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Pharmaceutical Composition of Valsartan: β-Cyclodextrin: Physico–Chemical and Characterization Anti-Hypertensive Evaluation

Valsartan, a water-insoluble drug, is mainly used in the treatment of hypertension albeit with reduced oral bioavailability. The aim of work was to develop a valsartan:β-cyclodextrin (VAL:β-CD) pharmaceutical composition in order to improve its water solubility and bioavailability. The VAL:β-CD comp...

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Detalles Bibliográficos
Autores principales: Eduardo de Matos Jensen, Carlos, dos Santos, Robson Augusto Souza, Denadai, Angelo Márcio Leite, Santos, Cynthia Fernandes Ferreira, Braga, Aline Nardoni Gonçalves, Sinisterra, Rubén Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257619/
https://www.ncbi.nlm.nih.gov/pubmed/20657427
http://dx.doi.org/10.3390/molecules15064067

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