Cu-Catalyzed Decarboxylative Borylation

[Image: see text] A simple method for the conversion of carboxylic acids to boronic esters via redox-active esters (RAEs) is reported using copper catalysis. The scope of this transformation is broad, and compared with the known protocols available, it represents the most inexpensive, rapid, and ope...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Shang, Ming, Lundberg, Helena, Feu, Karla S., Hecker, Scott J., Qin, Tian, Blackmond, Donna G., Baran, Phil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257631/
https://www.ncbi.nlm.nih.gov/pubmed/30505624
http://dx.doi.org/10.1021/acscatal.8b02928
Descripción
Sumario:[Image: see text] A simple method for the conversion of carboxylic acids to boronic esters via redox-active esters (RAEs) is reported using copper catalysis. The scope of this transformation is broad, and compared with the known protocols available, it represents the most inexpensive, rapid, and operationally simple option. In addition to a full exploration of the scope, a kinetic study was performed to elucidate substrate and reagent concentration dependences.

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