Cu-Catalyzed Decarboxylative Borylation

[Image: see text] A simple method for the conversion of carboxylic acids to boronic esters via redox-active esters (RAEs) is reported using copper catalysis. The scope of this transformation is broad, and compared with the known protocols available, it represents the most inexpensive, rapid, and ope...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jie, Shang, Ming, Lundberg, Helena, Feu, Karla S., Hecker, Scott J., Qin, Tian, Blackmond, Donna G., Baran, Phil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257631/
https://www.ncbi.nlm.nih.gov/pubmed/30505624
http://dx.doi.org/10.1021/acscatal.8b02928
_version_ 1783374358497984512
author Wang, Jie
Shang, Ming
Lundberg, Helena
Feu, Karla S.
Hecker, Scott J.
Qin, Tian
Blackmond, Donna G.
Baran, Phil S.
author_facet Wang, Jie
Shang, Ming
Lundberg, Helena
Feu, Karla S.
Hecker, Scott J.
Qin, Tian
Blackmond, Donna G.
Baran, Phil S.
author_sort Wang, Jie
collection PubMed
description [Image: see text] A simple method for the conversion of carboxylic acids to boronic esters via redox-active esters (RAEs) is reported using copper catalysis. The scope of this transformation is broad, and compared with the known protocols available, it represents the most inexpensive, rapid, and operationally simple option. In addition to a full exploration of the scope, a kinetic study was performed to elucidate substrate and reagent concentration dependences.
format Online
Article
Text
id pubmed-6257631
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-62576312018-11-29 Cu-Catalyzed Decarboxylative Borylation Wang, Jie Shang, Ming Lundberg, Helena Feu, Karla S. Hecker, Scott J. Qin, Tian Blackmond, Donna G. Baran, Phil S. ACS Catal [Image: see text] A simple method for the conversion of carboxylic acids to boronic esters via redox-active esters (RAEs) is reported using copper catalysis. The scope of this transformation is broad, and compared with the known protocols available, it represents the most inexpensive, rapid, and operationally simple option. In addition to a full exploration of the scope, a kinetic study was performed to elucidate substrate and reagent concentration dependences. American Chemical Society 2018-09-13 2018-10-05 /pmc/articles/PMC6257631/ /pubmed/30505624 http://dx.doi.org/10.1021/acscatal.8b02928 Text en Copyright © 2018 American Chemical Society This is an open access article published under a Creative Commons Attribution (CC-BY) License (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html) , which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
spellingShingle Wang, Jie
Shang, Ming
Lundberg, Helena
Feu, Karla S.
Hecker, Scott J.
Qin, Tian
Blackmond, Donna G.
Baran, Phil S.
Cu-Catalyzed Decarboxylative Borylation
title Cu-Catalyzed Decarboxylative Borylation
title_full Cu-Catalyzed Decarboxylative Borylation
title_fullStr Cu-Catalyzed Decarboxylative Borylation
title_full_unstemmed Cu-Catalyzed Decarboxylative Borylation
title_short Cu-Catalyzed Decarboxylative Borylation
title_sort cu-catalyzed decarboxylative borylation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257631/
https://www.ncbi.nlm.nih.gov/pubmed/30505624
http://dx.doi.org/10.1021/acscatal.8b02928
work_keys_str_mv AT wangjie cucatalyzeddecarboxylativeborylation
AT shangming cucatalyzeddecarboxylativeborylation
AT lundberghelena cucatalyzeddecarboxylativeborylation
AT feukarlas cucatalyzeddecarboxylativeborylation
AT heckerscottj cucatalyzeddecarboxylativeborylation
AT qintian cucatalyzeddecarboxylativeborylation
AT blackmonddonnag cucatalyzeddecarboxylativeborylation
AT baranphils cucatalyzeddecarboxylativeborylation

Ejemplares similares