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Solid-Phase Synthesis of Oligodeoxynucleotides Containing N(4)-[2-(t-butyldisulfanyl)ethyl]-5-methylcytosine Moieties
An efficient route for the synthesis of the phosphoramidite derivative of 5-methylcytosine bearing a tert-butylsulfanyl group protected thiol is described. This building block is used for the preparation of oligonucleotides carrying a thiol group at the nucleobase at the internal position of a DNA s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257692/ https://www.ncbi.nlm.nih.gov/pubmed/20720521 http://dx.doi.org/10.3390/molecules15085692 |