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Green One Pot Solvent-Free Synthesis of Pyrano[2,3-c]-Pyrazoles and Pyrazolo[1,5-a]Pyrimidines

Pyrano[2,3-c]pyrazoles are obtained via mixing ethyl acetoacetate, hydrazine hydrate, aldehydes or ketones and malononitrile in the absence of solvent. These same products were also obtained by reacting arylidenemalononitriles 3 with 3-methyl-2-pyrazolin-5-ones. NOE difference experiments confirmed...

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Detalles Bibliográficos
Autores principales: Al-Matar, Hamad M., Khalil, Khaled D., Adam, Aisha Y., Elnagdi, Mohamed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257727/
https://www.ncbi.nlm.nih.gov/pubmed/20877248
http://dx.doi.org/10.3390/molecules15096619

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