Cargando…

Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides

Applications of ring-closing alkene metathesis (RCM) in acyclic α- and β-peptides and closely related systems are reviewed, with a special emphasis on the structural and pharmacological effects of cyclization by RCM.

Detalles Bibliográficos
Autores principales: Jacobsen, Øyvind, Klaveness, Jo, Rongved, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257744/
https://www.ncbi.nlm.nih.gov/pubmed/20877250
http://dx.doi.org/10.3390/molecules15096638
Descripción
Sumario:Applications of ring-closing alkene metathesis (RCM) in acyclic α- and β-peptides and closely related systems are reviewed, with a special emphasis on the structural and pharmacological effects of cyclization by RCM.