Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides

Applications of ring-closing alkene metathesis (RCM) in acyclic α- and β-peptides and closely related systems are reviewed, with a special emphasis on the structural and pharmacological effects of cyclization by RCM.

Detalles Bibliográficos
Autores principales: Jacobsen, Øyvind, Klaveness, Jo, Rongved, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257744/
https://www.ncbi.nlm.nih.gov/pubmed/20877250
http://dx.doi.org/10.3390/molecules15096638
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author Jacobsen, Øyvind
Klaveness, Jo
Rongved, Pål
author_facet Jacobsen, Øyvind
Klaveness, Jo
Rongved, Pål
author_sort Jacobsen, Øyvind
collection PubMed
description Applications of ring-closing alkene metathesis (RCM) in acyclic α- and β-peptides and closely related systems are reviewed, with a special emphasis on the structural and pharmacological effects of cyclization by RCM.
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spelling pubmed-62577442018-12-06 Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides Jacobsen, Øyvind Klaveness, Jo Rongved, Pål Molecules Review Applications of ring-closing alkene metathesis (RCM) in acyclic α- and β-peptides and closely related systems are reviewed, with a special emphasis on the structural and pharmacological effects of cyclization by RCM. MDPI 2010-09-21 /pmc/articles/PMC6257744/ /pubmed/20877250 http://dx.doi.org/10.3390/molecules15096638 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Jacobsen, Øyvind
Klaveness, Jo
Rongved, Pål
Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides
title Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides
title_full Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides
title_fullStr Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides
title_full_unstemmed Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides
title_short Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides
title_sort structural and pharmacological effects of ring-closing metathesis in peptides
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257744/
https://www.ncbi.nlm.nih.gov/pubmed/20877250
http://dx.doi.org/10.3390/molecules15096638
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