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An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-α,β-unsaturated Esters
A microwave-assisted HWE olefination process of readily accessible aryl-alkyl ketones has been developed to provide a rapid access to (Z)-3,3-trisubstituted-α,β-unsaturated methyl esters, key building blocks for the synthesis of biologically active compounds.
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257757/ https://www.ncbi.nlm.nih.gov/pubmed/20802404 http://dx.doi.org/10.3390/molecules15095928 |
| _version_ | 1783374386044076032 |
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| author | Rossi, Daniela Baraglia, Anna Carnevale Serra, Massimo Azzolina, Ornella Collina, Simona |
| author_facet | Rossi, Daniela Baraglia, Anna Carnevale Serra, Massimo Azzolina, Ornella Collina, Simona |
| author_sort | Rossi, Daniela |
| collection | PubMed |
| description | A microwave-assisted HWE olefination process of readily accessible aryl-alkyl ketones has been developed to provide a rapid access to (Z)-3,3-trisubstituted-α,β-unsaturated methyl esters, key building blocks for the synthesis of biologically active compounds. |
| format | Online Article Text |
| id | pubmed-6257757 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2010 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-62577572018-12-06 An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-α,β-unsaturated Esters Rossi, Daniela Baraglia, Anna Carnevale Serra, Massimo Azzolina, Ornella Collina, Simona Molecules Communication A microwave-assisted HWE olefination process of readily accessible aryl-alkyl ketones has been developed to provide a rapid access to (Z)-3,3-trisubstituted-α,β-unsaturated methyl esters, key building blocks for the synthesis of biologically active compounds. MDPI 2010-08-27 /pmc/articles/PMC6257757/ /pubmed/20802404 http://dx.doi.org/10.3390/molecules15095928 Text en © 2010 by the authors; http://creativecommons.org/licenses/by/3.0/ licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
| spellingShingle | Communication Rossi, Daniela Baraglia, Anna Carnevale Serra, Massimo Azzolina, Ornella Collina, Simona An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-α,β-unsaturated Esters |
| title | An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-α,β-unsaturated Esters |
| title_full | An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-α,β-unsaturated Esters |
| title_fullStr | An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-α,β-unsaturated Esters |
| title_full_unstemmed | An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-α,β-unsaturated Esters |
| title_short | An Efficient Procedure Based on a MW-Assisted Horner–Wadsworth-Emmons Reaction for the Synthesis of (Z)-3,3-Trisubstituted-α,β-unsaturated Esters |
| title_sort | efficient procedure based on a mw-assisted horner–wadsworth-emmons reaction for the synthesis of (z)-3,3-trisubstituted-α,β-unsaturated esters |
| topic | Communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257757/ https://www.ncbi.nlm.nih.gov/pubmed/20802404 http://dx.doi.org/10.3390/molecules15095928 |
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