Cargando…

Overexpression of microRNA-183 promotes apoptosis of substantia nigra neurons via the inhibition of OSMR in a mouse model of Parkinson’s disease

The present study aimed to investigate the effect of microRNA-183 (miR-183) on substantia nigra neurons by targeting oncostatin M receptor (OSMR) in a mouse model of Parkinson’s disease (PD). The positive expression rates of OSMR and the apoptosis of substantia nigra neurons were detected by immunoh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Jin-Xia, Li, Yu, Wang, Sai-Nan, Chen, Xing-Chi, Lin, Lu-Lu, Zhang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257840/ https://www.ncbi.nlm.nih.gov/pubmed/30431059 http://dx.doi.org/10.3892/ijmm.2018.3982

Ejemplares similares

Mitochondrial dysfunction within the synapses of substantia nigra neurons in Parkinson’s disease
por: Reeve, Amy K., et al.
Publicado: (2018)

Irisin protects the substantia nigra dopaminergic neurons in the rat model of Parkinson’s disease
por: Zarbakhsh, Sam, et al.
Publicado: (2019)

Proteome analysis of human substantia nigra in Parkinson's disease
por: Werner, Cornelius J, et al.
Publicado: (2008)

Glucocerebrosidase Deficiency in Substantia Nigra of Parkinson Disease Brains
por: Gegg, Matthew E, et al.
Publicado: (2012)

Proliferation of Inhibitory Input to the Substantia Nigra in Experimental Parkinsonism
por: Faynveitz, Anna, et al.
Publicado: (2019)

Soemmerring and the Substantia Nigra
por: Faull, R. L. M, et al.
Publicado: (1968)

Substantia Nigra Integrity Correlates with Sequential Working Memory in Parkinson's Disease
por: Liu, Wenyue, et al.
Publicado: (2021)

Altered expression of genes involved in ganglioside biosynthesis in substantia nigra neurons in Parkinson’s disease
por: Schneider, Jay S.
Publicado: (2018)

Operant Self-Stimulation of Dopamine Neurons in the Substantia Nigra
por: Rossi, Mark A., et al.
Publicado: (2013)

Complement activation in the Parkinson's disease substantia nigra: an immunocytochemical study
por: Loeffler, David A, et al.
Publicado: (2006)

Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease
por: Dölle, Christian, et al.
Publicado: (2016)

Sex-Related Abnormalities in Substantia Nigra Lipids in Parkinson’s Disease
por: Seyfried, T. N., et al.
Publicado: (2018)

Oxidative stress in the aging substantia nigra and the etiology of Parkinson's disease
por: Trist, Benjamin G., et al.
Publicado: (2019)

Complementary Transcriptomic and Proteomic Analysis in the Substantia Nigra of Parkinson's Disease
por: Dong, Bao-hua, et al.
Publicado: (2021)

Imaging of Substantia Nigra in Parkinson’s Disease: A Narrative Review
por: Feraco, Paola, et al.
Publicado: (2021)

Ferroptosis-related factors in the substantia nigra are associated with Parkinson’s disease
por: Liu, Lei, et al.
Publicado: (2023)

Classification of Parkinson’s Disease in Patch-Based MRI of Substantia Nigra
por: Hussain, Sayyed Shahid, et al.
Publicado: (2023)

Inhibition of Calpain Attenuates Degeneration of Substantia Nigra Neurons in the Rotenone Rat Model of Parkinson’s Disease
por: Zaman, Vandana, et al.
Publicado: (2022)

Effect of Wenshen-Yanggan Decoction on Movement Disorder and Substantia Nigra Dopaminergic Neurons in Mice with Chronic Parkinson's Disease
por: Tang, Lili, et al.
Publicado: (2020)

Nano-imaging trace elements at organelle levels in substantia nigra overexpressing α-synuclein to model Parkinson’s disease
por: Lemelle, Laurence, et al.
Publicado: (2020)

NEAT1 is overexpressed in Parkinson’s disease substantia nigra and confers drug-inducible neuroprotection from oxidative stress
por: Simchovitz, Alon, et al.
Publicado: (2019)

Substantia nigra neuromelanin magnetic resonance imaging in patients with different subtypes of Parkinson disease
por: Wang, Lu, et al.
Publicado: (2021)

Eyes as Gateways for Environmental Light to the Substantia Nigra: Relevance in Parkinson's Disease
por: Romeo, Stefania, et al.
Publicado: (2014)

Transferrin protects against Parkinsonian neurotoxicity and is deficient in Parkinson’s substantia nigra
por: Ayton, Scott, et al.
Publicado: (2016)

Corrigendum to: Spatiotemporal changes in substantia nigra neuromelanin content in Parkinson’s disease
Publicado: (2020)

Homocysteine Intracerebroventricular Injection Induces Apoptosis in the Substantia Nigra Cells and Parkinson's Disease LikeBehavior in Rats
por: Ataie, Amin, et al.
Publicado: (2013)

Metabolic Disturbances in the Striatum and Substantia Nigra in the Onset and Progression of MPTP-Induced Parkinsonism Model
por: Lu, Yi, et al.
Publicado: (2018)

Gut microbiota relieves inflammation in the substantia nigra of chronic Parkinson's disease by protecting the function of dopamine neurons
por: Zhang, Tian, et al.
Publicado: (2022)

Picornavirus May Be Linked to Parkinson’s Disease through Viral Antigen in Dopamine-Containing Neurons of Substantia Nigra
por: Niklasson, Bo, et al.
Publicado: (2022)

Anti-apoptotic effect of Shudipingchan granule in the substantia nigra of rat models of Parkinson's disease
por: Ye, Qing, et al.
Publicado: (2016)

Substantia nigra micro-haemorrhage causing ipsilateral unilateral Parkinsonism and abnormal dopamine transporter scan uptake
por: Ghoneim, Aliaa, et al.
Publicado: (2020)

Pedunculopontine glutamatergic neurons control spike patterning in substantia nigra dopaminergic neurons
por: Galtieri, Daniel J, et al.
Publicado: (2017)

Electrophysiological evidence for functionally distinct neuronal populations in the human substantia nigra
por: Ramayya, Ashwin G., et al.
Publicado: (2014)

Activity-dependent regulation of NMDA receptors in substantia nigra dopaminergic neurones
por: Wild, Angela R, et al.
Publicado: (2014)

Verbascoside promotes the regeneration of tyrosine hydroxylase-immunoreactive neurons in the substantia nigra
por: Liang, Jian-qing, et al.
Publicado: (2016)

Implementation of deep neural networks to count dopamine neurons in substantia nigra
por: Penttinen, Anna‐Maija, et al.
Publicado: (2018)

Measuring the iron content of dopaminergic neurons in substantia nigra with MRI relaxometry
por: Brammerloh, Malte, et al.
Publicado: (2021)

The role of substantia nigra sonography in the differentiation of Parkinson’s disease and multiple system atrophy
por: Zhou, Hai-Yan, et al.
Publicado: (2018)

Explorative Combined Lipid and Transcriptomic Profiling of Substantia Nigra and Putamen in Parkinson’s Disease
por: Xicoy, Helena, et al.
Publicado: (2020)

Effects of Zhichan powder on signal transduction and apoptosis-associated gene expression in the substantia nigra of Parkinson's disease rats
por: Chen, Jiajun, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_40ndoua7akgcc4ae7cvgmd5h96