Cargando…

Spicatoside A in red Liriope platyphylla displays a laxative effect in a constipation rat model via regulating mAChRs and ER stress signaling

Red Liriope platyphylla extract (EtRLP) has been used as an oriental medicine for treatment of several chronic conditions, such as neurodegenerative disorders, diabetes, and obesity. To investigate the laxative activity of EtRLP, the levels of key constipation markers and their molecular regulators...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Ji Eun, Go, Jun, Lee, Hee Seob, Hong, Jin Tae, Hwang, Dae Youn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257849/ https://www.ncbi.nlm.nih.gov/pubmed/30387811 http://dx.doi.org/10.3892/ijmm.2018.3960

Ejemplares similares

Aqueous extracts of Liriope platyphylla induced significant laxative effects on loperamide-induced constipation of SD rats
por: Kim, Ji Eun, et al.
Publicado: (2013)

Metabolomics approach to serum biomarker for laxative effects of red Liriope platyphylla in loperamide-induced constipation of SD rats
por: Kim, Ji Eun, et al.
Publicado: (2019)

Laxative effects of Liriope platyphylla are tightly correlated with suppression of endoplasmic reticulum stress in loperamide-induced constipation of SD rats
por: Kim, Ji-Eun, et al.
Publicado: (2016)

Uridine stimulate laxative effect in the loperamide-induced constipation of SD rats through regulation of the mAChRs signaling pathway and mucin secretion
por: Kim, Ji Eun, et al.
Publicado: (2017)

Characterization of Changes in Global Genes Expression in the Distal Colon of Loperamide-Induced Constipation SD Rats in Response to the Laxative Effects of Liriope platyphylla
por: Kim, Ji Eun, et al.
Publicado: (2015)

Spicatoside A derived from Liriope platyphylla root ethanol extract inhibits hepatitis E virus genotype 3 replication in vitro
por: Park, Gayoung, et al.
Publicado: (2019)

Laxative Effect of Spicatoside A by Cholinergic Regulation of Enteric Nerve in Loperamide-Induced Constipation: ICR Mice Model
por: Kim, Ji Eun, et al.
Publicado: (2019)

Toxicity of red Liriope platyphylla manufactured by steaming process on liver and kidney organs of ICR mice
por: Choi, Sun-Il, et al.
Publicado: (2012)

Metabolic Analysis of Four Cultivars of Liriope platyphylla
por: Park, Chang Ha, et al.
Publicado: (2019)

Quercetin promotes gastrointestinal motility and mucin secretion in loperamide-induced constipation of SD rats through regulation of the mAChRs downstream signal
por: Kim, Ji Eun, et al.
Publicado: (2018)

Beneficial effects of ethanol extracts of Red Liriope platyphylla on vascular dysfunction in the aorta of spontaneously hypertensive rats
por: Lee, Young-Ju, et al.
Publicado: (2015)

Constipation in Tg2576 mice model for Alzheimer’s disease associated with dysregulation of mechanism involving the mAChR signaling pathway and ER stress response
por: Kim, Ji Eun, et al.
Publicado: (2019)

Mitigating Effects of Liriope platyphylla on Nicotine-Induced Behavioral Sensitization and Quality Control of Compounds
por: Yoon, Dahye, et al.
Publicado: (2020)

mAChRs activation induces epithelial-mesenchymal transition on lung epithelial cells
por: Yang, Kai, et al.
Publicado: (2014)

Effects of Steaming Time and Frequency for Manufactured Red Liriope platyphylla on the Insulin Secretion Ability and Insulin Receptor Signaling Pathway
por: Choi, Sun Il, et al.
Publicado: (2011)

Xanomeline displays concomitant orthosteric and allosteric binding modes at the M(4) mAChR
por: Burger, Wessel A. C., et al.
Publicado: (2023)

Red Liriope platyphylla stimulated the insulin secretion through the regulation of calcium concentration in rat insulinoma cells and animal models
por: Lee, Hye-Ryun, et al.
Publicado: (2013)

Phytochemicals and Estrogen-Receptor Agonists from the Aerial Parts of Liriope platyphylla
por: Tsai, Yu-Chi, et al.
Publicado: (2015)

Synthesis, Biological Evaluation, and Docking Studies of Antagonistic Hydroxylated Arecaidine Esters Targeting mAChRs
por: Kilian, Jonas, et al.
Publicado: (2022)

Precautionary effects of Red Liriope platyphylla on NGF secretion and Aβ42 deposition under the preclinical stage of Alzheimer's disease in Tg2576 mice
por: Choi, Sun-Il, et al.
Publicado: (2013)

Immunomodulatory Effects of Liriope Platyphylla Water Extract on Lipopolysaccharide-Activated Mouse Macrophage
por: Kim, Hye Kyung, et al.
Publicado: (2012)

Active Constituents from Liriope platyphylla Root against Cancer Growth In Vitro
por: Wang, Hui-Chun, et al.
Publicado: (2013)

The complete chloroplast genome sequence of a medicinal herb Liriope Platyphylla (Asparagaceae)
por: Lee, Yeonjeong, et al.
Publicado: (2019)

Characterization of the complete chloroplast genome of Liriope platyphylla (Asparagaceae: Nolinoideae) isolated in Korea
por: Jang, Ji-Hun, et al.
Publicado: (2020)

Effects of Red Liriope platyphylla on NGF secretion ability, NGF receptor signaling pathway and γ-secretase components in NSE/hAPPsw transgenic mice expressing Alzheimer's Disease
por: Choi, Sun-Il, et al.
Publicado: (2012)

Complement C3-Deficiency-Induced Constipation in FVB/N-C3(em1Hlee)/Korl Knockout Mice Was Significantly Relieved by Uridine and Liriope platyphylla L. Extracts
por: Song, Hee-Jin, et al.
Publicado: (2023)

Topical Application of Liriope platyphylla Extract Attenuates Dry Eye Syndrome Induced by Particulate Matter
por: Song, Su Jeong, et al.
Publicado: (2019)

Huperzine A lowers intraocular pressure via the M3 mAChR and provides retinal neuroprotection via the M1 mAChR: a promising agent for the treatment of glaucoma
por: Yu, Ping, et al.
Publicado: (2021)

Pharmacological Activities and Applications of Spicatoside A
por: Ramalingam, Mahesh, et al.
Publicado: (2016)

Correlation between laxative effects of uridine and suppression of ER stress in loperamide induced constipated SD rats
por: Kim, Ji Eun, et al.
Publicado: (2017)

Agonist mediated internalization of M(2 )mAChR is β-arrestin-dependent
por: Jones, Kymry T, et al.
Publicado: (2006)

Cell-type-specific synaptic modulation of mAChR on SST and PV interneurons
por: Chen, Huanxin, et al.
Publicado: (2023)

Aqueous extract of Liriope platyphylla, a traditional Chinese medicine, significantly inhibits abdominal fat accumulation and improves glucose regulation in OLETF type II diabetes model rats
por: Kim, Ji-Eun, et al.
Publicado: (2012)

Anti-inflammatory and antioxidant effects of muscarinic acetylcholine receptor (mAChR) activation in the rat hippocampus
por: Frinchi, Monica, et al.
Publicado: (2019)

Laxative Effects of Phlorotannins Derived from Ecklonia cava on Loperamide-Induced Constipation in SD Rats
por: Kim, Ji-Eun, et al.
Publicado: (2021)

Efficacy of Liriope platyphylla extract on improving respiratory function: A CONSORT-randomized, double-blind, placebo-controlled pilot trial
por: Won, Eun Sol, et al.
Publicado: (2022)

Vagal-mAChR4 signaling promotes Friend virus complex (FV)-induced acute erythroleukemia
por: Song, Shuting, et al.
Publicado: (2023)

Neuroprotective effects of Liriope platyphylla extract against hydrogen peroxide-induced cytotoxicity in human neuroblastoma SH-SY5Y cells
por: Park, Hee Ra, et al.
Publicado: (2015)

Efficacy of liriope platyphylla extract for improving respiratory functions: Study protocol for a randomized, double-blinded, placebo-controlled pilot trial
por: Jung, Ga Hyeon, et al.
Publicado: (2022)

Anti-Inflammatory and Antioxidant Activities of Lipophilic Fraction from Liriope platyphylla Seeds Using Network Pharmacology, Molecular Docking, and In Vitro Experiments
por: Truong, Van-Long, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6so2a0okbjv5dvid350p05si60