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MicroRNA-98 reduces amyloid β-protein production and improves oxidative stress and mitochondrial dysfunction through the Notch signaling pathway via HEY2 in Alzheimer’s disease mice

Alzheimer’s disease (AD) is a chronic neurodegenerative disease that often occurs at a slow pace yet deteriorates with time. MicroRNAs (miRs) have been demonstrated to offer novel therapeutic hope for disease treatment. The aim of the present study was to investigate the effect of miR-98 on amyloid...

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Detalles Bibliográficos
Autores principales: Chen, Fang-Zhou, Zhao, Ying, Chen, Hui-Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257854/
https://www.ncbi.nlm.nih.gov/pubmed/30365070
http://dx.doi.org/10.3892/ijmm.2018.3957