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Brain-derived neurotrophic factor inhibits hyperglycemia-induced apoptosis and downregulation of synaptic plasticity-related proteins in hippocampal neurons via the PI3K/Akt pathway

It is not known whether brain-derived neurotrophic factor (BDNF) protects hippocampal neurons from high glucose-induced apoptosis and/or synaptic plasticity dysfunction. The present study aimed to assess whether BDNF exerted a neuroprotective effect in rat hippocampal neurons exposed to high glucose...

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Detalles Bibliográficos
Autores principales: Zhong, Yuan, Zhu, Yitong, He, Ting, Li, Wei, Li, Qinjie, Miao, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257855/
https://www.ncbi.nlm.nih.gov/pubmed/30365051
http://dx.doi.org/10.3892/ijmm.2018.3933