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Survival status and predictors of mortality among children with severe acute malnutrition admitted to general hospitals of Tigray, North Ethiopia: a retrospective cohort study

OBJECTIVE: Despite the presence standard protocol for management of severe acute malnutrition case-fatality rates in African hospitals remain unacceptably high. The case in Ethiopia is not different from others. Therefore, this study was aimed to assess survival status and predictors of mortality am...

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Autores principales: Guesh, Gebremicael, Degu, Getu, Abay, Mebrahtu, Beyene, Berhe, Brhane, Ermyas, Brhane, Kalayu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257969/
https://www.ncbi.nlm.nih.gov/pubmed/30477540
http://dx.doi.org/10.1186/s13104-018-3937-x
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author Guesh, Gebremicael
Degu, Getu
Abay, Mebrahtu
Beyene, Berhe
Brhane, Ermyas
Brhane, Kalayu
author_facet Guesh, Gebremicael
Degu, Getu
Abay, Mebrahtu
Beyene, Berhe
Brhane, Ermyas
Brhane, Kalayu
author_sort Guesh, Gebremicael
collection PubMed
description OBJECTIVE: Despite the presence standard protocol for management of severe acute malnutrition case-fatality rates in African hospitals remain unacceptably high. The case in Ethiopia is not different from others. Therefore, this study was aimed to assess survival status and predictors of mortality among children with severe acute malnutrition admitted to stabilization centers of general hospitals in Tigray region, northern Ethiopia. A 24 months retrospective longitudinal study was conducted among 569 randomly selected medical records of children admitted to stabilizing centers. Both bi-variable and multivariable Cox regression analysis was conducted to identify predictors of mortality. Association was summarized using AHR, and statistical significances were declared at 95% CI and P-value < 0.05. RESULTS: During follow up, 456 [82%] of children had got cured, 37 [6.65%] were absconded and 21 [3.8%] were died. The overall mean survival time was 41.93 [95% CI 40.17–43.68] days. Impaired conscious level [AHR = 6.69, 95% CI 2.43–19.93], development of comorbidity after admission [AHR 12.71, 95% CI 2.79–57.94] and being urban in residence [AHR = 2.73, 95% CI 1.12–6.64] were predictors of mortality. Therefore, interventions to reduce further mortality should focus in children having impaired consciousness level and who developed comorbidity after admission. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3937-x) contains supplementary material, which is available to authorized users.
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spelling pubmed-62579692018-11-29 Survival status and predictors of mortality among children with severe acute malnutrition admitted to general hospitals of Tigray, North Ethiopia: a retrospective cohort study Guesh, Gebremicael Degu, Getu Abay, Mebrahtu Beyene, Berhe Brhane, Ermyas Brhane, Kalayu BMC Res Notes Research Note OBJECTIVE: Despite the presence standard protocol for management of severe acute malnutrition case-fatality rates in African hospitals remain unacceptably high. The case in Ethiopia is not different from others. Therefore, this study was aimed to assess survival status and predictors of mortality among children with severe acute malnutrition admitted to stabilization centers of general hospitals in Tigray region, northern Ethiopia. A 24 months retrospective longitudinal study was conducted among 569 randomly selected medical records of children admitted to stabilizing centers. Both bi-variable and multivariable Cox regression analysis was conducted to identify predictors of mortality. Association was summarized using AHR, and statistical significances were declared at 95% CI and P-value < 0.05. RESULTS: During follow up, 456 [82%] of children had got cured, 37 [6.65%] were absconded and 21 [3.8%] were died. The overall mean survival time was 41.93 [95% CI 40.17–43.68] days. Impaired conscious level [AHR = 6.69, 95% CI 2.43–19.93], development of comorbidity after admission [AHR 12.71, 95% CI 2.79–57.94] and being urban in residence [AHR = 2.73, 95% CI 1.12–6.64] were predictors of mortality. Therefore, interventions to reduce further mortality should focus in children having impaired consciousness level and who developed comorbidity after admission. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3937-x) contains supplementary material, which is available to authorized users. BioMed Central 2018-11-26 /pmc/articles/PMC6257969/ /pubmed/30477540 http://dx.doi.org/10.1186/s13104-018-3937-x Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Guesh, Gebremicael
Degu, Getu
Abay, Mebrahtu
Beyene, Berhe
Brhane, Ermyas
Brhane, Kalayu
Survival status and predictors of mortality among children with severe acute malnutrition admitted to general hospitals of Tigray, North Ethiopia: a retrospective cohort study
title Survival status and predictors of mortality among children with severe acute malnutrition admitted to general hospitals of Tigray, North Ethiopia: a retrospective cohort study
title_full Survival status and predictors of mortality among children with severe acute malnutrition admitted to general hospitals of Tigray, North Ethiopia: a retrospective cohort study
title_fullStr Survival status and predictors of mortality among children with severe acute malnutrition admitted to general hospitals of Tigray, North Ethiopia: a retrospective cohort study
title_full_unstemmed Survival status and predictors of mortality among children with severe acute malnutrition admitted to general hospitals of Tigray, North Ethiopia: a retrospective cohort study
title_short Survival status and predictors of mortality among children with severe acute malnutrition admitted to general hospitals of Tigray, North Ethiopia: a retrospective cohort study
title_sort survival status and predictors of mortality among children with severe acute malnutrition admitted to general hospitals of tigray, north ethiopia: a retrospective cohort study
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257969/
https://www.ncbi.nlm.nih.gov/pubmed/30477540
http://dx.doi.org/10.1186/s13104-018-3937-x
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